PurR

• Description: purine repressor
  
  

Gene name	purR
Synonyms	yabI
Essential
Product	transcriptional regulator
Function	negative regulation of the purine operons ( purEKBCLQFMNHD, purA)
MW, pI	31 kDa, 5.771
Gene length, protein length	855 bp, 285 aa
Immediate neighbours
Gene sequence (+200bp)	Protein sequence
Genetic context

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: PRPP acts as inducer, binding results in release of PurR from the operator

• Interactions: PurR-Prs

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry:

• E.C. number:

Additional information

requires YabJ for in vivo activity

Expression and regulation

• Operon: purR-yabJ

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed