Difference between revisions of "PurF"

From SubtiWiki
Jump to: navigation, search
Line 82: Line 82:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P00497 P00497]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P00497 P00497]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU06490]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU06490 BSU06490]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.4.2.14 2.4.2.14]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.4.2.14 2.4.2.14]

Revision as of 23:45, 13 May 2009

  • Description: glutamine phosphoribosyldiphosphate amidotransferase

Gene name purF
Synonyms purB
Essential no
Product glutamine phosphoribosyldiphosphate amidotransferase
Function purine biosynthesis
MW, pI 51 kDa, 5.873
Gene length, protein length 1428 bp, 476 aa
Immediate neighbours purL, purM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PurF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1GPH, 1AO0 (complex with ADP and GMP)

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Gerth et al. (2008) Clp-dependent proteolysis down-regulates central metabolic pathways in glucose-starved Bacillus subtilis. J Bacteriol 190:321-331 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed