Difference between revisions of "PurE"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO<sub>2</sub> (according to Swiss-Prot)
  
 
* '''Protein family:''' AIR carboxylase family (according to Swiss-Prot)
 
* '''Protein family:''' AIR carboxylase family (according to Swiss-Prot)

Revision as of 13:06, 23 May 2009

  • Description: phosphoribosylaminoimidazole carboxylase (ATP-dependent)

Gene name purE
Synonyms
Essential no
Product phosphoribosylaminoimidazole carboxylase (ATP-dependent)
Function purine biosynthesis
MW, pI 17 kDa, 5.199
Gene length, protein length 486 bp, 162 aa
Immediate neighbours yebG, purK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PurE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2 (according to Swiss-Prot)
  • Protein family: AIR carboxylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed