Difference between revisions of "PurD"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU06530
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P12039 P12039]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P12039 P12039]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU06530 BSU06530]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU06530]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.4.13 6.3.4.13]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.4.13 6.3.4.13]

Revision as of 11:59, 3 June 2009

  • Description: phosphoribosylglycinamide synthetase

Gene name purD
Synonyms
Essential no
Product phosphoribosylglycinamide synthetase
Function purine biosynthesis
MW, pI 45 kDa, 4.604
Gene length, protein length 1266 bp, 422 aa
Immediate neighbours purH, yezC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PurD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU06530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide (according to Swiss-Prot)
  • Protein family: ATP-grasp domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of adenine or adenosine(PurR) PubMed
    • repressed in the presence of guanine(G-box) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed