Difference between revisions of "PurC"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU06450 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P12046 P12046] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P12046 P12046] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU06450] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.2.6 6.3.2.6] | * '''E.C. number:''' [http://www.expasy.org/enzyme/6.3.2.6 6.3.2.6] | ||
Revision as of 10:54, 3 June 2009
- Description: phosphoribosylaminoimidazole succinocarboxamide synthase
| Gene name | purC |
| Synonyms | |
| Essential | no |
| Product | phosphoribosylaminoimidazole succinocarboxamide synthase |
| Function | purine biosynthesis |
| MW, pI | 27 kDa, 4.875 |
| Gene length, protein length | 723 bp, 241 aa |
| Immediate neighbours | purB, purS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU06450
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (according to Swiss-Prot)
- Protein family: SAICAR synthetase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P12046
- KEGG entry: [3]
- E.C. number: 6.3.2.6
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
