Difference between revisions of "PucR"

From SubtiWiki
Jump to: navigation, search
(Genes/ operons controlled by PucR {{PubMed|12029039}})
Line 50: Line 50:
  
  
 +
 +
= Categories containing this gene/protein =
 +
{{SubtiWiki category|[[utilization of nucleotides]]}},
 +
{{SubtiWiki category|[[transcription factors and their control]]}}
 
=The protein=
 
=The protein=
  

Revision as of 19:04, 30 November 2010

  • Description: transcriptional regulator of puc genes

Gene name pucR
Synonyms yunI
Essential no
Product transcriptional regulator of puc genes
Function regulation of purine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 60 kDa, 6.188
Gene length, protein length 1593 bp, 531 aa
Immediate neighbours pucH, pucJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU32420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

utilization of nucleotides, transcription factors and their control

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cdaR family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes/ operons controlled by PucR PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by purine nucleotides (effector: allantoin) (PucR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ken-ichi Yoshida, Hirotake Yamaguchi, Masaki Kinehara, Yo-hei Ohki, Yoshiko Nakaura, Yasutaro Fujita
Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box.
Mol Microbiol: 2003, 49(1);157-65
[PubMed:12823818] [WorldCat.org] [DOI] (P p)

Jaclyn L Brandenburg, Lewis V Wray, Lars Beier, Hanne Jarmer, Hans H Saxild, Susan H Fisher
Roles of PucR, GlnR, and TnrA in regulating expression of the Bacillus subtilis ure P3 promoter.
J Bacteriol: 2002, 184(21);6060-4
[PubMed:12374841] [WorldCat.org] [DOI] (P p)

Lars Beier, Per Nygaard, Hanne Jarmer, Hans H Saxild
Transcription analysis of the Bacillus subtilis PucR regulon and identification of a cis-acting sequence required for PucR-regulated expression of genes involved in purine catabolism.
J Bacteriol: 2002, 184(12);3232-41
[PubMed:12029039] [WorldCat.org] [DOI] (P p)

A C Schultz, P Nygaard, H H Saxild
Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator.
J Bacteriol: 2001, 183(11);3293-302
[PubMed:11344136] [WorldCat.org] [DOI] (P p)