Difference between revisions of "PucE"
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** repressed by purine nucleotides (effector: allantoin) ([[PucR]]) {{PubMed|12029039}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [PucR]]: transcription repression {{PubMed|12029039}} | + | ** [[PucR]]: transcription repression {{PubMed|12029039}} |
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 16:31, 28 December 2009
- Description: xanthine dehydrogenase
| Gene name | pucE |
| Synonyms | yurB |
| Essential | no |
| Product | xanthine dehydrogenase |
| Function | purine utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Purine catabolism, Nucleotides (regulation) | |
| MW, pI | 18 kDa, 6.127 |
| Gene length, protein length | 519 bp, 173 aa |
| Immediate neighbours | pucM, pucD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU32470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Xanthine + NAD+ + H2O = urate + NADH (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32143
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
