PtsG

• Description: A major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
  
  

Gene name	ptsG
Synonyms	ptsX, crr
Essential	no
Product	glucose-specific enzyme IICBA component
Function	glucose transport and phosphorylation
MW, pI	75,3 kDa, 5.40
Gene length, protein length	2097 bp, 699 amino acids
Immediate neighbours	gltC, ptsH
Gene sequence (+200bp)	Protein sequence
Genetic context File:GenE context.gif

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • 11x Transmembrane Domain (16–36, 89–109, 139–159, 180–200, 233–253, 283–303, 313–333, 338–358, 365–385, 388–408)
  • PTS EIIC type-1 Domain ( 1-424)
  • PTS EIIB type-1 Domain (439–520)
  • PTS EIIA type-1 Domain (568–672)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane protein

Database entries

• Structure:

• Swiss prot entry: [3]

• KEGG entry: [4]

• E.C. number: [5]

Additional information

hpr can be phosphorylated at His-46 and alternatively at Ser-12

Expression and regulation

• Operon: ptsGHI, ptsHI
• Sigma factor:

• Regulation:

• Regulatory mechanism: ptsG: riboswitch (GlcT-dependent)

• Additional information:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed