Difference between revisions of "PtpZ"

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* '''Description:''' phosphotyrosin protein phosphatase, antagonist to PtkA <br/><br/>
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* '''Description:''' phosphotyrosin protein phosphatase, antagonist to [[PtkA]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
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|-
|style="background:#ABCDEF;" align="center"| '''Product''' || phosphotyrosin protein phosphatase, <br/>antagonist to PtkA  
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|style="background:#ABCDEF;" align="center"| '''Product''' || phosphotyrosin protein phosphatase, <br/>antagonist to [[PtkA]]
 
|-
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || protein tyrosine dephosphorylation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || protein tyrosine dephosphorylation

Revision as of 19:16, 17 January 2010

  • Description: phosphotyrosin protein phosphatase, antagonist to PtkA

Gene name ptpZ
Synonyms ywqE
Essential no
Product phosphotyrosin protein phosphatase,
antagonist to PtkA
Function protein tyrosine dephosphorylation
MW, pI 28 kDa, 6.66
Gene length, protein length 762 bp, 254 aa
Immediate neighbours ywqF, ptkA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwqE context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Locus tag: BSU36240

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
  • Protein family: cpsB/capC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ivan Mijakovic, Lucia Musumeci, Lutz Tautz, Dina Petranovic, Robert A Edwards, Peter Ruhdal Jensen, Tomas Mustelin, Josef Deutscher, Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
J Bacteriol: 2005, 187(10);3384-90
[PubMed:15866923] [WorldCat.org] [DOI] (P p)

Ivan Mijakovic, Sandrine Poncet, Grégory Boël, Alain Mazé, Sylvie Gillet, Emmanuel Jamet, Paulette Decottignies, Christophe Grangeasse, Patricia Doublet, Pierre Le Maréchal, Josef Deutscher
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.
EMBO J: 2003, 22(18);4709-18
[PubMed:12970183] [WorldCat.org] [DOI] (P p)