PsdR

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  • Description: two-component response regulator, induction of psdA-psdB in response to lipid II-binding lantibiotics, such as nisin and gallidermin

Gene name psdR
Synonyms yvcP
Essential no
Product two-component response regulator
Function resistance against toxic peptides
Gene expression levels in SubtiExpress: psdR
Interactions involving this protein in SubtInteract: PsdR
MW, pI 27 kDa, 4.676
Gene length, protein length 711 bp, 237 aa
Immediate neighbours psdS, yvzJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YvcP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PsdR expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

This gene is a member of the following regulons

The PsdR regulon: psdA-psdB

The gene

Basic information

  • Locus tag: BSU34720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by PsdS on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed