Difference between revisions of "Psd"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybfM]]'', ''[[ybfN]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybfM]]'', ''[[ybfN]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02290 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02290 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02290 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02290 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02290 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02290 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:psd_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:psd_context.gif]]

Revision as of 09:22, 14 May 2013

  • Description: phosphatidylserine decarboxylase

Gene name psd
Synonyms
Essential no
Product phosphatidylserine decarboxylase
Function biosynthesis of phospholipids
Gene expression levels in SubtiExpress: psd
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 29 kDa, 7.27
Gene length, protein length 789 bp, 263 aa
Immediate neighbours ybfM, ybfN
Sequences Protein DNA DNA_with_flanks
Genetic context
Psd context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Psd expression.png




























Categories containing this gene/protein

biosynthesis of lipids, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigX regulon

The gene

Basic information

  • Locus tag: BSU02290

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Phosphatidyl-L-serine = phosphatidylethanolamine + CO2 (according to Swiss-Prot)
  • Protein family: Type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Letal I Salzberg, John D Helmann
Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.
J Bacteriol: 2008, 190(23);7797-807
[PubMed:18820022] [WorldCat.org] [DOI] (I p)

Ayako Nishibori, Jin Kusaka, Hiroshi Hara, Masato Umeda, Kouji Matsumoto
Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes.
J Bacteriol: 2005, 187(6);2163-74
[PubMed:15743965] [WorldCat.org] [DOI] (P p)

Min Cao, John D Helmann
The Bacillus subtilis extracytoplasmic-function sigmaX factor regulates modification of the cell envelope and resistance to cationic antimicrobial peptides.
J Bacteriol: 2004, 186(4);1136-46
[PubMed:14762009] [WorldCat.org] [DOI] (P p)

K Matsumoto, M Okada, Y Horikoshi, H Matsuzaki, T Kishi, M Itaya, I Shibuya
Cloning, sequencing, and disruption of the Bacillus subtilis psd gene coding for phosphatidylserine decarboxylase.
J Bacteriol: 1998, 180(1);100-6
[PubMed:9422599] [WorldCat.org] [DOI] (P p)