Protein kinases and phosphatases

These enzymes phosphorylate or dephosphorylate other proteins. By definition, they use ATP (or GTP) as the phosphoryl group donor (as opposed to phosphotransferases of the phosphotranferase system and the phosphorelay).

Protein kinases

Protein serine kinases

• HprK (has also phosphorylase activity)
• PrkC
• PrkD
• RsbT
• RsbW
• SpoIIAB
• YabT

Protein tyrosine kinases

• PtkA
• EpsB: similar to PtkA, but has probably no kinase activity

Protein kinases of two-component systems

• ComP
• DegS
• DesK
• LiaS
• YdfH
• YfiJ
• YhcY
• YvfT
• YxjM
• BceS
• CssS
• NatK
• PhoR
• ResE
• WalK
• YbdK
• YcbM
• YclK
• YkoH
• YrkO
• YvcQ
• YvrG
• YxdK
• CheA
• CitS
• DctS
• GlnK
• MalK
• LytS
• YesM
• YwpD
• KinA
• KinB
• KinC
• KinD
• KinE

Protein phosphatases

Protein serine phosphatases

• PrpC
• RsbP
• RsbU
• RsbX
• SpoIIE

Protein tyrosine phosphatases

• PtpZ
• YfkJ
• YwlE

Protein aspartate phosphatases controlling the phosphorelay

• Spo0E: dephosphorylation of Spo0A
• YisI: dephosphorylation of Spo0A
• YnzD: dephosphorylation of Spo0A
• RapA: dephosphorylation of Spo0F
• RapB: dephosphorylation of Spo0F
• RapE: dephosphorylation of Spo0F
• RapH: dephosphorylation of Spo0F

Related Lists

• phosphoproteins
• two-component systems

Reviews

Sandro F F Pereira, Lindsie Goss, Jonathan Dworkin
Eukaryote-like serine/threonine kinases and phosphatases in bacteria.
Microbiol Mol Biol Rev: 2011, 75(1);192-212
[PubMed:21372323] [WorldCat.org] [DOI] (I p)

Michał Obuchowski
[Serine-threonine protein phosphatases from Bacillus subtilis]. [Serynowo-treoninowe fosfatazy białkowe w Bacillus subtilis.]
Postepy Biochem: 2005, 51(1);95-104
[PubMed:16209347] [WorldCat.org] (P p)