Program

Tuesday, April 29, 2014

▪ 8:00 – 9.00 REGISTRATION ▪ 9:00 – 9:10 – Welcome Introduction

Session I Metabolism

CHAIR: Jan Maarten van Dijl

• 9:10 – 9:25 – Ken-ichi Yoshida, Kobe University, Japan
  • Inositol dehydrogenases in Geobacillus kaustophilus are regulated by a Crh homolog but not by glucose
• 9:30 – 9:45 – Matthieu Jules, INRA, MICALIS, France
  • New regulation and catabolic repression of the uptake of gluconeogenic carbon sources
• 9:50 – 10:05 – Uwe Völker, University Medicine Greifswald, Germany
  • Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective.
• 10:10 – 10:25 – Raphael Michna, General Microbiology, Göttingen, Germany
  • SubtiWiki and its compagnons: Tools for data integration of Bacillus subtilis
• 10:30 – 10:50 – COFFEE BREAK

Session II Synthetic Biology and Secretion

CHAIR: Nicola Stanley-Wall

• 10:50 – 11:05 – Philippe Noirot,INRA, France
  • Streamlining the Bacillus subtilis genome: from proof-of-concept to cell factories
• 11:10 – 11:25 – Iolanda Ferro, University of Potsdam, Germany
  • Emerging role of tRNA charging for protein expression in Bacillus licheniformis
• 11:30 – 11:45 – Marcel Hillebrand, DSM, Delft, Netherlands
  • Signal sequence fusion libraries for increased enzyme production
• 11:50 – 12:05 – Jolanda Neef, University of Groningen (UMCG), the Netherlands
  • A novel expression platform for the production of cell wall-bound and secreted staphylococcal antigens
• 12:10 – 12:25 – Giulia Barbieri, University of Pavia, Italy
  • CodY regulates the expression of two proteases in B. subtilis
• 12:30 – 14:00 LUNCH (+ BACIP MEETING)

Session III: Stress response and regulation

CHAIR: Leendert Hamoen

• 14:00 – 14:15 – Thorsten Mascher, Ludwig-Maximilians-Universität München, Germany
  • Cannibalism Stress Response in Bacillus subtilis
• 14:20 – 14:35 – Sandra Maaß, Ernst-Moritz-Arndt Universität Greifswald, Germany
  • Absolute protein quantification of stress and starvation responses in Bacillus subtilis.
• 14:40 – 14:55 – Tamara Hoffmann, Philipps-University Marburg, Germany
  • Balancing the osmotic gradient: transcriptional control of opuAA expression in response to osmotic stress and the cytoplasmic compatible solute pool
• 15:00 – 15:15 – Michaela Wenzel, University of Amsterdam, the Netherlands
  • Antimicrobial peptides elicit a hypoosmotic shock response in Bacillus subtilis.
• 15:20 – 15:35 – Georg Fritz, LMU Munich, Germany
  • Interdependence between different layers of the cell envelope stress response in Bacillus subtilis.
• 15:40 – 15:55 – Niclas Nordholt, VU University Amsterdam, the Netherlands
  • How Bacillus subtilis tunes its growth rate when it gets hot
• 16:00 – 16:20 – COFFEE BREAK

Session IV: Sporulation

CHAIR: Jörg Stülke

• 16:20 – 16:35 – Tony Wilkinson, University of York, UK
  • Structure function studies of the cell fate determining protein SpoIIE
• 16:40 – 16:55 – Rizlan Bernier-Latmani, EPFL, Lausanne, Switzerland
  • Desulfotomaculum: a genus of spore-forming bacteria involved in S and Fe cycling
• 17:00 – 17:15– Jan Jamroskovic, EPFL, Lausanne, Switzerland
  • Quantitative study of DPA and calcium transport during sporulation of Bacillus subtilis.
• 17:20 – 17:35 – Robyn Eijlander, University of Groningen, NL
  • The role of SpoVT in sporulation of Bacilli – two sides of the same coin
• 17.40 – 17.55– Liesbet Thijs, Kemin Europa NV, Belgium
  • The beneficial effects of Bacillus subtilis PB6 on performance of laying hens
• 18.00 – 19.00 BACELL STEERING GROUP MEETING

Wednesday, April 30, 2014

Session V: Sporulation and other spore formers

CHAIR: Kevin Devine

• 9:00 – 9:15 – Didier Lereclus, INRA, France
  • A bifunctional quorum sensor couples necrotrophism and sporulation in Bacillus thuringiensis
• 9:20 – 9:35 – Sylvie Nessler, University Paris, France
  • Structure-function analysis of the bifunctional quorum sensor NprR from Bacillus thuringiensis
• 9:40 – 9:55 – Emilie Verplaetse, INRA MICALIS, France
  • Dynamics of virulence, necrotrophism and sporulation states in a Bacillus thuringiensis population at the cell-level
• 10:00 – 10:15 – Monika Ehling-Schulz, University of Veterinary Medicine Vienna, Austria
  • Pathometabolism of emetic Bacillus cereus
• 10:20 – 10:40 – COFFEE BREAK

Session VI: Regulation

CHAIR: Philippe Noirot

• 10:40 – 10:55 – Kevin Devine, Trinity College Dublin, Ireland
  • New Insights into PhoP-PhoR Expression and Regulation in Bacillus subtilis
• 11:00 – 11:15 – Marie-Françoise Noirot-Gros, INRA, Jouy-en-Josas, France
  • Tyrosine Kinase Interaction Network in Bacillus subtilis Reveals New Substrates, Kinase Activators and Extensive Functional Cross-talk Among Kinases.
• 11:20 – 11:35 – Susanne Gebhard, Ludwig-Maximilians-Universität München, Germany
  • Communication between ABC transporters and histidine kinases in antimicrobial peptide resistance modules
• 11:40 – 11:55 – Libor Krásný, MBU AVČR, Praha, Czech Republic
  • Characterization of HelD, a new interacting partner of RNA polymerase from Bacillus subtilis
• 12:00 – 12:15 – Ruben Mars, University of Groningen (UMCG), the Netherlands
  • Noise promotion of autorepressed AbrB by a small regulatory RNA generates heterogeneity in growth rate of Bacillus subtilis
• 12:20 – 12:35 – Ulrike Mäder, University Medicine Greifswald, Germany
  • AureoWiki - the repository of the Staphylococcus aureus research and annotation community
• 12:40 – 13:40 – LUNCH

Session VII: Regulation & Replication

CHAIR: Henrik Strahl

• 13:40 – 13:55 – Sara Kesel, Ludwig-Maximilians-University, DE
  • Immediate and heterogeneous response of the LiaF-LiaS-LiaR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin
• 14:00 – 14:15 –Jakob Engman, Lund University, SE
  • Aggregation of the YjbH adaptor protein as a mechanism of Spx regulation.
• 14:20 – 14:35 – Fabian Commichau, University of Göttingen, DE
  • Essential genes in Bacillus subtilis: a re-evaluation after 10 years
• 14:40 – 14:55– Thorsten Mascher, Ludwig-Maximilians-University, DE
  • (Tools for studying the) Regulatory dynamics of peptide antibiotic detoxification modules in Bacillus subtilis
• 15:00 – 15:15 – Vladimir Bidnenko, INRA, Jouy en Josas, FR
  • Distinct activities of co-essential Bacillus subtilis flap-endonucleases, Pol I and YpcP, in DNA replication and repair
• 15:20 – 15:35 – Panos Soultanas, University of Nottingham, UK
  • Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex during lagging strand DNA replication in Bacillus subtilis
• 15:40 – 16:00 – COFFEE BREAK

Session VIII: Division

CHAIR: Alan Nielson

• 16:00 – 16:15 – Peter Graumann, Universitat Freiburg, DE
  • Movement of up to 3.4mm long MreB filaments at various angles underneath the cell membrane and their intrinsic membrane affinity
• 16:20 – 16:35 – Hiraku Takada, Tokyo University of Agriculture, Japan
  • Involvement of essential lipid synthetic enzyme, PlsX, in the cell division machinery
• 16:40 – 16:55 – Ilkay Celik, Newcastle University, UK
  • Bacillus minimal divisome
• 17:00 – 17:15 – Robert Cleverley, Newcastle University, UK
  • Structure of the major divisome protein EzrA
• 17:20 – 17:35 – Alex Dajkovic, University of California Irvine, USA
  • Organization of FtsZ polymers in living Bacillus subtilis cells
• 17:40 – 17:55 – Romain Mercier, Newcastle University, UK
  • Excess membrane synthesis drives a primitive mode of cell proliferation

= END OF MEETING = Biofilms