Program

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Revision as of 16:45, 15 April 2012 by Jstuelk (talk | contribs) (Tuesday April 24th 2012 – Morning)
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Tuesday April 24th 2012 – Morning

  • 8:00-8:45 - REGISTRATION
  • 9:00-9:10 – Welcome Introduction Kevin Devine

Session I: Modeling and Networks

CHAIR: Sierd Bron

  • 9:10-9:30 – BACELL Systems – Past, Present, Future
  • 9:30-9:50 – Unraveling the Small Regulatory RNA Network of Bacillus subtilis
    • Ruben Mars (University Medical Center Groningen)
  • 9:50-10:10 – A Computational Stressosome Model Consolidates Hypotheses about Environmental Activation of SigB the General Stress response
    • Ulf Liebal (University of Rostock)
  • 10:10-10:30 – Reconciling Molecular Regulatory Mechanisms with Noise Patterns of Bacterial Metabolic Promoters in Induced and Repressed States
    • Matthieu Jules (Institut Micalis, INRA)
  • 10:30 – 11:00 – COFFEE BREAK

Session II: Cell Wall

CHAIR: Colin Harwood

  • 11:00-11:20 – The WalR/WalK, PhoP/PhoR and SigI/RsgI Regulatory Systems of Bacillus subtilis Cooperate to Control Cell Wall Metabolism during Growth and Under Stress Conditions
    • Letal Salzberg (Trinity College Dublin)
  • 11:20-11:40 – Adaptation of Bacillus subtilis to High Salinity: Osmotic Induction of the Cell Wall Hydrolase YqiI
    • Kathleen Fischer (Philipps-Universität Marburg)
  • 11:40-12:00 – Regulatory and Cellular Dynamics of the Lia-Response of Bacillus subtilis
  • 12:00-12:20 – SepF is a New Membrane Anchor for the Key Cell Division Protein FtsZ
    • Ilkay Celik (Newcastle University)
  • 12:20-12:40 – The Bacterial MreB Cytoskeleton Organizes the Cell Membrane
    • Henrik Strahl (Newcastle University)
  • 12:40 – 14:20 LUNCH (+ BACIP MEETING)

Tuesday April 24th 2012 – Afternoon

Session III: Adaptation, Sporulation and DNA Replication

CHAIR: Ulrike Mäder

  • 14:20-14:40 – Selecting Better Bet Hedging Bacillus Strains
    • Jeroen Siebring (University of Groningen)
  • 14:40-15:00 – Spore Coat Proteins: Self-Assembly Properties and Protein-Protein Interactions
    • Daniela Krajčíková (Slovak Academy of Sciences)
  • 15:00-15:20 – Spo0A links DNA Replication with Sporulation by Direct Binding to the Origin of Replication in Bacillus subtilis
    • Mirjam Boonstra (University of Groningen)
    • 15:20-15:40 – DSB Repair Pathway is Required for Viability of the SMC-ScpA-ScpB Depleted Strain
    • Etienne Dervyn (Institut Micalis, INRA)
  • 15:40-16:10 - COFFEE BREAK

Session IV: Antibiotics

CHAIR: Eugenio Ferrari

  • 16:10-16:30 – Regulated Expression of a Multidrug-ABC Transporter – The yheH-yheI-yheJ Operon
    • Ewoud Reilman (University of Groningen)
  • 16:30-16:50 – Signal Transduction in Antimicrobial Peptide Detoxification Modules of Bacillus subtilis: Interaction between ABC Transport and Sensor Kinase
    • Susanne Gebhard (Ludwig-Maximilians-University Munich)
  • 16:50-17:10 – Structure-Function Relationship of the Lantibiotic Immunity-Protein SpaI
    • Sophie Bochmann (Goethe University Frankfurt)
  • 17:10-17:30 – Structure, Biosynthesis and Properties of Kurstakins, Nonribosomal Lipopeptides from Bacillus spp.
    • Philippe Jacques (Universite de Lille)

17.30-18.30 BACELL STEERING GROUP MEETING

19:30 – WINE RECEPTION

20:00 - DINNER

Wednesday April 25th 2012 - Morning

Session V: Application

CHAIR: Jörg Stülke

  • 9:00-9:20 – Bacillus subtilis Cell Factory Producing Scyllo-Inositol, A Potential Therapeutic Agent for Alzheimer’s Disease
  • 9:20-9:40 – Developing an Enzyme Discovery Tool for Bacillus subtilis
    • Tjeerd van Rij (DSM)
  • 9:40 – 10:00 - Use of Bacillus amyloliquefaciens for Control of Plant Stress
    • Johan Meijer (University of Uppsala)
  • 10:00 – 10:20 – Phenotypic Heterogeneity during Heterologous Protein Production in Bacillus megaterium
    • Rebekka Biedendieck (Technische Universität Braunschweig)
  • 10:20-10:40 – Absolute Protein Quantification - Application in Bacillus subtilis

10:40-11:00 - COFFEE BREAK

Session VI: RNA Metabolism and Regulation

CHAIR: Uwe Völker

  • 11:00-11:20 – Three Essential Ribonucleases RNase Y, J1 and III Control the Abundance of a Majority of B. subtilis mRNAs
  • 12:00 – 12:20 – Requirements for the High-Frequency Activation of the Cryptic gudB Glutamate Dehydrogenase Gene in Bacillus subtilis
    • Fabian Commichau (Georg-August-Universität Göttingen)
  • 12:20-12:40 – The Anaerobic Formation of Acetoin Regulated by the Transcriptional Regulator AlsR – Part of pH Homeostasis in Bacillus subtilis

12:40-14:00 – LUNCH

Wednesday April 25th 2012 - Afternoon

EU BaSynthec Synthetic Biology Symposium

CHAIR: Kevin Devine

  • 14:00-14:10 – Introduction – Philippe Noirot (INRA)
  • 14:10-14:40 – Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis - Naotake Ogasawara (Nara Institute)
  • 14:40-15:10 – Computational and Bioinformatics Approaches to Enabling Synthetic Biology - Anil Wipat (Newcastle University)
  • 15:10-15:40 – Highly Modified Peptides by Synthetic Biology Approaches - Oscar Kuipers (Groningen University)
  • 15:40-16:10 – COFFEE BREAK
  • 16:10-16:40 – Bacillus subtilis Minimal Genome Work in Europe - Philippe Noirot (INRA)
  • 16:40-17:10 – View of Novozymes on Synthetic Biology - Allen Kent Nielsen (Novozymes)
  • 17:10-17:40 – View of DSM on Synthetic Biology - Zoltán Prágai (DSM)
  • 17:40-17:50 – Wrap up / end of workshop – Philippe Noirot (INRA)


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