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| − | =Sunday, June 19, 2011 – Afternoon= | + | =Tuesday April 24th 2012 – Morning= |
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| + | * 8:00-8:45 - REGISTRATION |
| − | * 2:00 Welcome remarks – [[Jim Hoch]] | + | * 9:00-9:10 – Welcome Introduction [[Kevin Devine]] |
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| − | ==Physiology==
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| − | CHAIR: [[Josef Deutscher]]
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| − | * 2:15 – 2:30 T1, Elaine Milohanic, INRA and AgroParis Tech, Thiverval-Grignon, France
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| − | ** [[ManR]] regulates the expression of the main ''Listeria monocytogenes'' glucose/mannose transporter and uses a second glucose transporter as substrate sensor.
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| − | * 2:30 – 2:45 T2, [[Boris Görke]], Dept. of General Microbiology, Georg-August University of Göttingen, Göttingen, Germany
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| − | ** [[Crh]], the homolog of the phosphor-carrier protein HPr, regulates a glycolytic bypass in ''Bacillus subtilis''. | |
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| − | * 2:45 – 3:00 T3, Jean-Michel Jault, Institut de Biologie Structurale, Grenoble, France
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| − | ** The unusual activity of a [[GTP-binding proteins|GTPase]] from ''Bacillus subtilis'', [[YphC]] (or [[EngA]]), involved in ribosome biogenesis.
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| − | * 3:00 – 3:15 T4, Yuka Kazo, Laboratory of Molecular Genetics, Department of Life Science, Rikkyo University, Tokyo, Japan
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| − | ** Analysis of dimerization of 70S ribosome, and ''[[yvyD]]'' gene during stationary phase in ''Bacillus subtilis''.
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| − | * 3:15 – 3:30 T5, Donald A. Morrison, Dept. of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
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| − | ** Regulation of the competence regulon in Group A and Group B streptococci: Pyogenic Type II ComR receptors recognize small species-specific peptide pheromones when expressed in a heterologous host.
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| − | * 3:30 – 3:45 T6, Nathalie Campo, Centre national de la Recherche Scientifique, Toulouse, France
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| − | ** X-state (competence) development causes transient cell cycle alterations in ''Streptococcus pneumoniae''.
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| − | * 3:45 – 4:00 T7, Maria C. Mansilla, Instituto de Biología Molecular y Celular, Univ. Nac.de Rosario, Rosario, Argentina
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| − | ** A novel pathway for lipoic acid synthesis in Gram-positive bacteria.
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| − | * 4:00 – 4:15 T8, [[Jörg Stülke]], Dept. of General Microbiology, Georg-August- Univeristy Göttingen, Göttingen, Germany
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| − | ** A novel factor controlling bistability in ''Bacillus subtilis'': The [[YmdB]] protein affects [[biofilm formation]] and [[motility and chemotaxis|motility]].
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| − | ==Genome Engineering ==
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| − | CHAIR: Mike Rasmussen
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| − | * 4:45 – 5:00 T9, Robert A. Britton, Dept. of Microbiology and Molecular Genetics, Michigan State University, East Lansing Michigan, USA
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| − | ** Recombineering in lactic acid bacteria.
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| − | * 5:00 – 5:15 T10, Ghislain Schyns, DSM Nutritional Products, Ltd., Basel, Switzerland
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| − | ** Learning from probiotics to improve biological availability of feed enzymes.
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| − | * 5:15 – 5:30 T11, Sébastien Potot, DSM Nutritional Products, Biotechnology, Basel, Switzerland
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| − | ** Mixing bacterial genomes to identify critical mutations in ''Bacillus subtilis'' industrial strains.
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| − | * 5:30 – 5:45 T12, Philippe Jacques, Université Lille, France
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| − | ** Environmental factors and pleiotropic regulators influence homologous compound pattern of mycosubtilin produced by ''Bacilius subtilis'' ATCC 6633.
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| − | * 5:45 – 6:00 T13, [[Philippe Noirot]], INRA, Jouy en Josas, France
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| − | ** Systematic identification of dispensable genome parts in ''Bacillus subtilis'' coupled with metabolic model reconstruction.
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| − | ==Welcome Reception - 7:00 – 9:00 – Grand Hotel & La Pace==
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| − | =Monday, June 20, 2011 – Morning=
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| − | ==Cell Wall I==
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| − | CHAIR: [[Kevin Devine]]
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| − | * 8:15 – 9:00, [[Jeff Errington]], Centre for Bacterial Cell Biology, Newcastle University, Newcastle-upon-Tyne, United Kingdom
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| − | ** Keynote Lecture: Emergence and proliferation of ''B. subtilis'' L-forms.
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| − | * 9:00 – 9:15 T14, Olaf Schneewind, Dept. of Microbiology, University of Chicago, Chicago, Illinois, USA
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| − | ** LytN, a murein hydrolase in the cross wall compartment of ''Staphylococcus aureus'', is required for bacterial growth and envelope assembly.
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| − | * 9:15 – 9:30 T15, Hèléne Bierne, Institut Pasteur, Unité des interactions bactéries-cellules, Inserm, Paris, France
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| − | ** A regulated switch from helical to polar localization of ''Listeria monocytogenes'' cell wall-anchored proteins.
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| − | * 9:30 – 9:45 T16 [[Sven Halbedel]], Dept. of Bacterial Infections, Robert Koch Institute, Wernigerode, Germany
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| − | ** A role for the membrane curvature sensor [[DivIVA]] in cell separation and virulence of ''Listeria monocytogenes''.
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| − | * 9:45 – 10:00 T17, Teresa Costa, ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
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| − | ** Control of ''Bacillus subtilis'' cell shape by the novel cytoskeletal element [[RodZ]].
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| − | * 10:00 – 10:15 T18, Julia Domínguez-Escobar, Max Planck Institute of Biochemistry, Martinsried, Germany
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| − | **Processive movement of [[MreB]]-associated cell wall biosynthetic complexes in bacteria. ''In vivo'' visualization of sidewall biosynthetic machineries in ''Bacillus subtilis''.
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| − | * 10:15 – 10:30 T19, [[Anne Galinier]], Université de la Méditerranée, Marseille, France
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| − | ** The [[YvcK]] protein is required for morphogenesis via localization of [[ponA|PBP1]] under gluconeogenic growth conditions in ''Bacillus subtilis''.
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| | | | |
| − | ==Cell Wall II== | + | ==Session I: Modeling and Networks == |
| − | CHAIR: [[Jeff Errington]] | + | CHAIR: [[Sierd Bron]] |
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| − | * 11:00 – 11:15 T20, Letal Salzberg, Smurfit Institute of Genetics, Trintiy College Dublin, Dublin, Ireland
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| − | ** [[WalR]]-[[WalK]] ([[YycF]]-[[YycG]])-mediated control of cell wall metabolism in ''Bacillus subtilis'': linking autolysins and actin-like proteins.
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| − | * 11:15 – 11:30 T21, Hiraku Takada, Tokyo University of Agriculture, Tokyo, Japan | + | * 9:10-9:30 – BACELL Systems – Past, Present, Future |
| − | ** Involvement of essential lipid synthetic enzyme, [[PlsX]], in the cell division machinery. | + | ** [[Jan Maarten van Dijl]] (University Medical Center Groningen) |
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| − | * 11:30 – 11:45 T22, Maria-Halima Laaberki, Dept. of Microbiology and Immunology, Columbia University, New York, New York, USA
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| − | ** The unexpected role of O-acetylation of peptidoglycan in cell separation and S-layer anchoring in ''Bacillus anthracis''.
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| − | * 11:45 – 12:00 T23, Michel-Yves Mistou, INRA, Institut Micalis, Jouy-en-Josas, France | + | * 9:30-9:50 – Unraveling the [[ncRNA|Small Regulatory RNA]] Network of ''Bacillus subtilis'' |
| − | ** Outer polysaccharide pellicle: a structural component of Gram positive bacteria cell wall.
| + | ** Ruben Mars (University Medical Center Groningen) |
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| − | * 12:00 – 12:15 T24, [[Rick Lewis]], Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom
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| − | ** The decoration of peptidoglycan by teichoic acids: the missing enzymatic step revealed by X-ray crystallography? | |
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| − | =Monday, June 20, 2011 – Afternoon=
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| − | ==Structure==
| + | * 9:50-10:10 – A Computational [[Stressosome]] Model Consolidates Hypotheses about Environmental Activation of [[SigB]] the General Stress response |
| − | CHAIR: [[Jim Hoch]]
| + | ** Ulf Liebal (University of Rostock) |
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| − | * 2:00 – 2:15 T25, Wayne F. Anderson, Northwestern University CSGID, Chicago, Illinois USA | + | * 10:10-10:30 – Reconciling Molecular Regulatory Mechanisms with Noise Patterns of Bacterial Metabolic Promoters in Induced and Repressed States |
| − | ** Applying structural genomics – revealing the bacterial surface one protein structure at a time. | + | ** Matthieu Jules (Institut Micalis, INRA) |
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| − | * 2:15 – 2:30 T26, Catarina G. Fernandes, ITQB, Universidade Nova de Lisboa, Oeiras, Portugal | + | * 10:30 – 11:00 – COFFEE BREAK |
| − | ** From the crystal structure of the [[Tgl]] transglutaminase to the cross-linking of the spore surface layers.
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| − | * 2:30 – 2:45 T27, [[Claes von Wachenfeldt]], Dept. of Biology, Lund University, Lund, Sweden
| + | == Session II: [[Cell wall degradation/ turnover|Cell Wall]] == |
| − | ** Redox sensing by [[Rex]] family repressors.
| + | CHAIR: [[Colin Harwood]] |
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| − | * 2:45 – 3:00 T28, Marion Boudes, IBBMC, Université Paris-Sud, Orsay, France | + | * 11:00-11:20 – The [[WalR]]/[[WalK]], [[PhoP]]/[[PhoR]] and [[SigI]]/[[RsgI]] Regulatory Systems of ''Bacillus subtilis'' Cooperate to Control Cell Wall Metabolism during Growth and Under Stress Conditions |
| − | ** Structural and functional study of ComE, a key actor in ''S. pneumoniae'' competence.
| + | ** Letal Salzberg (Trinity College Dublin) |
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| − | * 3:00 – 3:15 T29, [[Hendrik Szurmant]], Dept. of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA | + | * 11:20-11:40 – Adaptation of ''Bacillus subtilis'' to High Salinity: Osmotic Induction of the Cell Wall Hydrolase [[YqiI]] |
| − | ** [[Two-component systems|Sensor histidine kinase]] signaling: An active conformation deduced from integrating genomics, molecular dynamics and mutagenesis. | + | ** Kathleen Fischer (Philipps-Universität Marburg) |
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| − | ==[[Sporulation proteins|Sporulation]]/ [[germination]]==
| + | * 11:40-12:00 – Regulatory and Cellular Dynamics of the Lia-Response of ''Bacillus subtilis'' |
| − | CHAIR: [[Charles Moran]]
| + | ** [[Thorsten Mascher]] (Ludwig-Maximilians-University Munich) |
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| − | * 3:45 – 4:00 T30, Michael Young, Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, United Kindom | + | * 12:00-12:20 – [[SepF]] is a New Membrane Anchor for the Key [[Cell Division]] Protein [[FtsZ]] |
| − | ** Multiple orphan histidine kinases interact directly with [[Spo0A]] to control the initiation of endospore formation in ''Clostridium acetobutylicum''.
| + | ** Ilkay Celik (Newcastle University) |
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| − | * 4:00 – 4:15 T31, Lei Shi, INRA-AgroParis Tech, Micalis Institute, Jouy-en-Josas, France | + | * 12:20-12:40 – The Bacterial [[MreB]] Cytoskeleton Organizes the Cell Membrane |
| − | ** Phosphorylated bacterial recombinase checks chromosome integrity during spore formation. | + | ** Henrik Strahl (Newcastle University) |
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| − | * 4:15 – 4:30 T32, [[Patrick Piggot]], Dept. Microbiol. & Immunol., Temple University School of Medicine, Philadelphia, Pennsylvania, USA | + | * 12:40 – 14:20 LUNCH (+ BACIP MEETING) |
| − | ** Compartmentalization of [[SigE|σE]] Activity During Sporulation of ''Bacillus subtilis'': Much Ado About What?
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| − | * 4:30 – 4:45 T33, [[Adriano Henriques]], ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
| + | =Tuesday April 24th 2012 – Afternoon= |
| − | ** A negative feedback loop that limits the ectopic activation of a cell type-specific sporulation [[sigma factor]] of ''Bacillus subtilis''.
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| − | * 4:45 – 5:00 T34, Thierry Doan, Dept. of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, USA
| + | == Session III: Adaptation, [[Sporulation]] and [[DNA replication|DNA Replication]] == |
| − | ** Bacterial membrane fission during sporulation in ''Bacillus subtilis''.
| + | CHAIR: [[Ulrike Mäder]] |
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| − | * 5:00 – 5:15 T35, [[Tony Wilkinson]], Dept. of Chemistry, University of York, UK | + | * 14:20-14:40 – Selecting Better Bet Hedging [[Bacillus]] Strains |
| − | ** Structural and Interaction Studies of an Intercellular Complex Mediating Engulfment during Sporulation in ''B. subtilis''. | + | ** Jeroen Siebring (University of Groningen) |
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| − | * 5:15 – 5:30 T36, [[Patrick Eichenberger]], Center for Genomics and Systems Biology, Dept. of Biology, New York University, New York, USA | + | * 14:40-15:00 – Spore Coat Proteins: Self-Assembly Properties and Protein-Protein [[SubtInteract|Interactions]] |
| − | ** A Spatial and Temporal map of the ''Bacillus subtilis'' Spore Coat. | + | ** Daniela Krajčíková (Slovak Academy of Sciences) |
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| − | * 5:30 – 5:45 T37, Alex Ter Beek, Molecular Biology & Microbial Food Safety, University of Amsterdam, The Netherlands | + | * 15:00-15:20 – [[Spo0A]] links [[DNA replication|DNA Replication]] with [[Sporulation]] by Direct Binding to the Origin of Replication in ''Bacillus subtilis'' |
| − | ** Live-cell imaging of aerobic bacteria: a tool to assess and model heterogeneous [[germination]] & outgrowth of ''Bacillus subtilis'' spores.
| + | ** Mirjam Boonstra (University of Groningen) |
| | | | |
| − | ==Poster Session I==
| + | ** 15:20-15:40 – DSB Repair Pathway is Required for Viability of the [[smc|SMC]]-[[ScpA]]-[[ScpB]] Depleted Strain |
| − | * 5:45 – 7:45, Palazzo dei Congressi Sala Alba | + | ** Etienne Dervyn (Institut Micalis, INRA) |
| | | | |
| − | =Tuesday, June 21, 2011– Morning=
| + | * 15:40-16:10 - COFFEE BREAK |
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| − | ==Pathogenic Sporeformers - Clostridia== | + | == Session IV: Antibiotics == |
| − | CHAIR: Mike Young | + | CHAIR: [[Eugenio Ferrari]] |
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| − | * 8:30 – 9:15, Neil Fairweather, Centre for Molecular Microbiology and Infection, Dept. of Life Sciences, Imperial College London, London, UK | + | * 16:10-16:30 – Regulated Expression of a Multidrug-[[ABC transporters|ABC Transporter]] – The ''[[yheH]]-[[yheI]]-[[yheJ]]'' Operon |
| − | ** Keynote Lecture: The cell wall of ''Clostridium difficile'' – is variability a key to pathogenesis?
| + | ** Ewoud Reilman (University of Groningen) |
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| − | * 9:15 – 9:30 T38, [[Linc Sonenshein]], Tufts University School of Medicine, Boston, Massachusetts, USA | + | * 16:30-16:50 – Signal Transduction in Antimicrobial Peptide Detoxification Modules of ''Bacillus subtilis'': Interaction between [[ABC transporters|ABC Transport]] and Sensor Kinase |
| − | ** Regulation of ''Clostridium difficile'' virulence. | + | ** Susanne Gebhard (Ludwig-Maximilians-University Munich) |
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| − | * 9:30 – 9:45 T39, Zhen Zhang, Faculty of Veterinary Medicine, University of Helsinki, Finland | + | * 16:50-17:10 – Structure-Function Relationship of the Lantibiotic Immunity-Protein [[SpaI]] |
| − | ** A [[Two-component systems|Two-Component System]] Negatively Regulates Botulinum Neurotoxin Expression.
| + | ** Sophie Bochmann (Goethe University Frankfurt) |
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| − | * 9:45 – 10:00 T40, Eric A. Johnson, University of Wisconsin, Madison, Wisconsin, USA | + | * 17:10-17:30 – Structure, Biosynthesis and Properties of Kurstakins, Nonribosomal Lipopeptides from [[Bacillus]] spp. |
| − | ** Identification, Purification and Characterization of Botulinum Neurotoxin BoNT/A Subtype Toxins. | + | ** [[Philippe Jacques]] (Universite de Lille) |
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| − | * 10:00 – 10:15 T41, Stephen Melville, Dept. of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA
| + | == 17.30-18.30 BACELL STEERING GROUP MEETING == |
| − | ** Spatial and temporal linkage of type IV pili assembly and division septum formation in ''Clostridium perfringens''.
| + | == 19:30 – WINE RECEPTION == |
| | + | == 20:00 - DINNER == |
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| − | * 10:15 – 10:30 T42, Jon Marles-Wright, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK
| + | = Wednesday April 25th 2012 - Morning = |
| − | ** Towards an understanding of the anatomy of Clostridial bacterial microcompartments.
| + | == Session V: Application == |
| | + | CHAIR: [[Jörg Stülke]] |
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| − | ==Pathogenic Sporeformers - ''Bacillus anthracis''==
| + | * 9:00-9:20 – ''Bacillus subtilis'' Cell Factory Producing Scyllo-Inositol, A Potential Therapeutic Agent for Alzheimer’s Disease |
| − | CHAIR: Olaf Schneewind
| + | ** [[Ken-ichi Yoshida]] (Kobe University) |
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| − | * 11:00 – 11:15 T43, Theresa M. Koehler, Dept. Microbiol. and Molec. Genet., University of Texas Medical School, Houston, Texas, USA | + | * 9:20-9:40 – Developing an Enzyme Discovery Tool for ''Bacillus subtilis'' |
| − | ** Modulation of the ''Bacillus anthracis'' Secretome.
| + | ** Tjeerd van Rij (DSM) |
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| − | * 11:15 – 11:30 T44, Susanne Pohl, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK | + | * 9:40 – 10:00 - Use of ''Bacillus amyloliquefaciens'' for Control of Plant Stress |
| − | ** The secondary secretion pathway in ''Bacillus anthracis''.
| + | ** Johan Meijer (University of Uppsala) |
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| − | * 11:30 – 11:45 T45, Agnès Fouet, Toxines et Pathogénie Bactériennes, Institut Pasteur, Paris, France | + | * 10:00 – 10:20 – Phenotypic Heterogeneity during Heterologous Protein Production in ''Bacillus megaterium'' |
| − | ** ''Bacillus anthracis'' virulence regulator AtxA mediates bicarbonate induction of toxin gene expression.
| + | ** Rebekka Biedendieck (Technische Universität Braunschweig) |
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| − | * 11:45 – 12:00 T46, [[Colin Harwood]], Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK | + | * 10:20-10:40 – Absolute Protein Quantification - Application in ''Bacillus subtilis'' |
| − | ** Are superoxide ions a key environmental signal for the ''Bacillus anthracis'' pathogenic life cycle?
| + | ** [[Dörte Becher]] (Ernst-Moritz-Arndt Universität Greifswald) |
| | | | |
| − | =Tuesday, June 21, 2011– Morning=
| + | 10:40-11:00 - COFFEE BREAK |
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| − | ==[[Transcription]] Regulation I== | + | == Session VI: RNA Metabolism and Regulation == |
| − | CHAIR: Terry Koehler | + | CHAIR: [[Uwe Völker]] |
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| − | * 2:00 – 2:15 T47, Kris Ann Baker, Dept. of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA | + | * 11:00-11:20 – Three Essential Ribonucleases [[rny|RNase Y]], [[rnjA|J1]] and [[rnc|III]] Control the Abundance of a Majority of ''B. subtilis'' mRNAs |
| − | ** Transcription anti-termination by a phosphorylated response regulator and cobalamin-dependent termination at a B12 [[riboswitch]] contribute to ethanolamine utilization in ''Enterococcus faecalis''.
| + | ** [[Ciaran Condon|Ciarán Condon]] (Institut de Biologie Physico-Chimique CNRS) |
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| − | * 2:15 – 2:30 T48, [[Harald Putzer]], Institut de Biologie Physico-Chimique, Paris, France | + | * 11:20-11:40 – The Effects of [[RpoE]] and [[HelD]] on [[RNA polymerase|RNA Polymerase]] from ''Bacillus subtilis'' |
| − | ** The roles of [[RNases]] [[rny|Y]] and [[rnjA|J]] in mRNA metabolism in ''Bacillus subtilis''.
| + | ** [[Libor Krasny|Libor Krásný]] (Academy of Sciences of the Czech Republic) |
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| − | * 2:30 – 2:45 T49, Jean-Christophe Giard, Laboratoire de Microbiologie de l’Environnement, University of Caen, Caen, France | + | * 11:40 – 12:00 – Dynamic Localization of an [[LicT|RNA-Binding Transcription Factor]] in ''Bacillus subtilis'' |
| − | ** First experimental genome-wide identification of [[ncRNA|small non-coding RNAs]] in the opportunistic pathogen ''Enterococcus faecalis'' V583.
| + | ** Fabian Rothe (University of Göttingen) |
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| − | * 2:45 – 3:00 T50, [[Peter Lewis]], School of Environmental and Life Sciences, University of Newcastle, Callaghan, Australia
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| − | ** Structure/Function analysis of epsilon: A new subunit of Gram positive [[RNA polymerase|RNA polymerases]].
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| − | | |
| − | * 3:00 – 3:15 T51, Olivier Delumeau, INRA, Micalis Institute, Jouy-en-Josas, France
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| − | ** The dynamic protein partnership of [[RNA polymerase]] in ''Bacillus subtilis''.
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| − | * 3:15 – 3:30 T52, [[Thorsten Mascher]], Department of Biology, Ludwig-Maximilians-University, Munich, Germany | |
| − | ** Extracytoplasmic function (ECF) [[sigma factors]] in gram-positive bacteria: Heading for the unknown. | |
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| − | ==[[Transcription]] Regulation II==
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| − | CHAIR: [[Linc Sonenshein]]
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| − | * 4:00 –4:15 T53, Michael J. Federle, Dept. of Med. Chem. Pharmacognosy, The University of Illinois at Chicago, Chicago, Illinois, USA
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| − | ** Rgg [[transcription factors]] are a new class of pheromone response effectors in streptococci.
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| − | * 4:15 – 4:30 T54, Rozenn Gardan, INRA UMR1319 Micalis, Jouy-en-Josas, France
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| − | ** Rgg-associated small hydrophobic peptides: A new family of pheromones involved in [[quorum sensing]] in streptococci.
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| − | * 4:30 – 4:45 T55, Isabelle Poquet, Microbiologie de l’Alimentation au service de la Santé, UMR 1319 Micalis, Jouy-en-Josas, France
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| − | ** ''Lactococcus lactis'' ZitR is a zinc responsive repressor active in low, non-toxic zinc concentrations ''in vivo''.
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| − | * 4:45 – 5:00 T56, Thomas Dubois, INRA, UMR1319 Micalis, Jouy-en-Josas, France
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| − | ** The NprR quorum sensor is required for the saprophytic way of life of ''Bacillus cereus''.
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| − | * 5:00 – 5:15 T57, Boris R. Belitsky, Tufts University School of Medicine, Boston, Massachusetts, USA
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| − | ** Multiple modes of DNA binding and regulation by ''Bacillus subtilis'' [[CodY]].
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| − | | |
| − | ==Poster Session II==
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| − | * 5:30 – 7:30, Palazzo dei Congressi Sala Alba
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| − | | |
| − | =Wednesday, June 22, 2011– Morning=
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| − | ==Pathogenesis II==
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| − | CHAIR: Agnes Fouet
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| − | * 8:30 – 8:45 T58, Hèléne Bierne, Institut Pasteur, Unité des Interactions Bactéries Cellules – Inserm, Paris, France
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| − | ** ''Listeria monocytogenes'' hijacks the chromatin-remodeling machinery to modulate type III interferon responses.
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| − | * 8:45 – 9:00 T59, Jennifer Mitchell, University College Dublin, Dublin, Ireland
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| − | ** CD36 is a receptor for the adherence of Gram positive pathogens to platelets.
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| − | * 9:00 – 9:15 T60, Marco Rinaldo Oggioni, University of Siena, Siena, Italy
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| − | ** A single bacterium at the origin of invasive pneumococcal disease: macrophage clearance defines the bottleneck during the first hours of infection.
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| − | * 9:15 – 9:30 T61, Johannes Huebner, Division of Infectious Diseases, University Hospital Freiburg, Freiburg, Germany
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| − | ** Genetic loci involved in surface carbohydrate production in Enterococci.
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| − | * 9:30 – 9:45 T62, Kimberly Kline, Dept. of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
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| − | ** Molecular requirements for localized secretion and sortase-assembled virulence factor biogenesis in ''Enterococcus faecalis''.
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| − | * 9:45 – 10:00 T63, Hailyn V. Nielsen, University of Washington School of Medicine, St. Louis, Missouri, USA
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| − | ** Minor tip and base pilins EbpA and EbpB contribute to ''E. faecalis'' virulence in a murine model of foreign body-associated urinary tract infection.
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| − | ==[[Resistance against toxins/ antibiotics|Antimicrobial resistance]]==
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| − | CHAIR: [[Jan Maarten van Dijl]]
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| − | * 10:30 – 10:45 T64, Emma L. Denham, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands
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| − | ** Unraveling the bactericidal mechanism of the glycopeptides sublancin 168.
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| − | | |
| − | *10:45 – 11:00 T65, Alexandra A. Roberts, School of Pharmacy, University of East Anglia, Norwich, UK
| |
| − | ** FosB is a bacillithiol-S-transferase that confers bacillithiol-dependent fosfomycin resistance on the Gram positive pathogen ''Staphylococcus aureus''.
| |
| − | | |
| − | * 11:00 – 11:15 T66, [[Tarek Msadek]], Biology of Gram-positive Pathogens, Department of Microbiology, Institut Pasteur, Paris, France
| |
| − | ** The [[ABC transporters|ABCs]] of bacitracin and nisin resistance in ''Staphylococcus aureus''.
| |
| − | | |
| − | * 11:15 – 11:30 T67, Susanne Gebhard, Department of Biology, Ludwig-Maximilians University Munich, Munich, Germany
| |
| − | ** Co-evolution of and signaling by [[ABC transporters]] and [[two-component systems|two-component regulatory systems]] as [[Resistance against toxins/ antibiotics|resistance modules against antimicrobial peptides]] in Firmicutes bacteria.
| |
| − | | |
| − | * 11:30 – 11:45 T68, Willem van Schaik, Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
| |
| − | ** Comprehensive identification of genes required for resistance to β-lactam antibiotics in the nosocomial pathogen ''Enterococcus faecium''.
| |
| − | | |
| − | * 11:45 – 12:00 T69, Mary K. Phillips-Jones, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK
| |
| − | ** ''In vitro'' activation and inhibition of the intact quorum membrane sensor FsrC involved in virulence in ''Enterococcus faecalis'' V583
| |
| − | | |
| − | =Wednesday, June 22, 2011– Afternoon=
| |
| − | | |
| − | ==Pathogenesis III==
| |
| − | CHAIR: Johannes Huebner
| |
| − | | |
| − | * 2:00 – 2:15 T70, Breck A. Duerkop, Department of Immunology, University of Texas, Dallas, Texas, USA
| |
| − | ** Bacteriophage production by ''Enterococcus faecalis'' in the mammalian intestine.
| |
| − | | |
| − | * 2:15 – 2:30 T71, Renata Matos, ITQB, Oeiras, Portugal; Institut Micalis, INRA, Jouy-en-Josas, France; Universidad Complutense de Madrid, Spain
| |
| − | ** ''Enterococcus faecalis'' V583 prophages are induced by low concentrations of antibiotic.
| |
| − | | |
| − | * 2:30 – 2:45 T72, Pascale S. Guiton, Dept. of Mol. Microbiol. & Microbial Pathogenesis, Washington University, St. Louis, Missouri, USA
| |
| − | ** Characterization of the host response to ''Enterococcus faecalis'' mediated catheter-associated urinary tract infection.
| |
| − | | |
| − | * 2:45 – 3:00 T73, Ravi P.N. Mishra, Novartis Vaccines and Diagnostics, Siena, Italy
| |
| − | ** Ferric Hydroxamate-binding Lipoprotein FhuD2 protects against ''Staphylococcus aureus'' infection.
| |
| − | | |
| − | ==Pathogenesis IV: Streptococci==
| |
| − | CHAIR: Paul Sullam
| |
| − | | |
| − | * 3:30 – 3:45 T74, Heaven Oliver-Kozup, Dept. Microbiol., Immunol. & Cell Biol., West Virginia University, Morgantown, West Virginia, USA
| |
| − | ** Targeted binding of the surface adhesion Sel1 to a spliced variant of cellular fibronectin expressed in wounded tissue.
| |
| − | | |
| − | * 3:45 – 4:00 T75, Kathryn M. Gold, Dept. of Cell Biology & Molecular Genetics, University of Maryland, College Park, Maryland, USA
| |
| − | ** Characterization of the TrxSR [[two-component systems|Two-Component Signal Transduction System]] that Activates Virulence in ''Streptococcus pyogenes''.
| |
| − | | |
| − | * 4:00 – 4:15 T76, Vijay Pancholi, Department of Pathology, The Ohio State University, Columbus, Ohio, USA
| |
| − | ** A novel transcriptional regulatory role of [[sdhA|SDH]]/[[gapA|GAPDH]] in ''Streptococcus pyogenes'' [[metabolism]] and virulence.
| |
| − | | |
| − | * 4:15 – 4:30 T77, Sean D. Reid, Dept. Microbiol. & Immunol., Wake Forest University, Winston-Salem, North Carolina, USA
| |
| − | ** Insights into the regulation of Group A Streptococcal [[biofilm formation]] and dispersal and the impact on disease severity.
| |
| − | | |
| − | * 4:30 – 4:45 T78, Ravin Seepersaud, Division of Infectious Disease, University of California, San Francisco, California, USA
| |
| − | ** The accessory Sec protein Asp2 is required for both the optimal glycosylation and transport of GspB, the serine rich repeat glycoprotein adhesion of ''Streptococcus gordonii''.
| |
| − | | |
| − | * 4:45 – 5:00 T79, Françoise Rul, INRA, Micalis Institute, Jouy-en-Josas, France
| |
| − | ** The proteomic signature of ''Streptococcus thermophilus'' in the digestive environment provides clues to lactic acid bacteria/host interactions.
| |
| − | | |
| − | * 5:00 – 5:15 T80, Philippe Glaser, Laboratoire Evolution et Génomique Bactériennes, Institut Pasteur, Paris, France
| |
| − | ** Emergence of a ''Streptococcus agalactiae'' lineage hypervirulent in fish by reductive evolution.
| |
| − | | |
| − | * 5:15 – 5:30 T81, Shaynoor Dramsi, Institut Pasteur, Unité de Biologie des Bactéries Pathogènes à Gram-Positif, Paris, France
| |
| − | ** Role of ''Streptococcus gallolyticus'' Pil1 pilus in endocarditis.
| |
| − | | |
| − | ==Reception and Banquet - 6:30 – 9:30 – Grand Hotel & La Pace==
| |
| − | | |
| − | =Thursday, June 23, 2011– Morning=
| |
| − | | |
| − | ==Stress I==
| |
| − | CHAIR: [[Erhard Bremer]]
| |
| − | | |
| − | * 8:30 – 8:45 T82, Terry A. Krulwich, Dept. Pharmacol. Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, USA
| |
| − | ** In accord with the “no free lunch” principle, adaptations of alkaliphilc ''Bacillus'' that support constitutive readiness for an alkali challenge reduce fitness near neutral pH.
| |
| − | | |
| − | * 8:45 – 9:00 T83, Masahiro Ito, Graduate School of Life Science, Toyo University, Oura-gun, Gunma, Japan
| |
| − | ** A novel K+-stimulated flagellar motor from alkaliphilic ''Bacillus''.
| |
| − | | |
| − | * 9:00 – 9:15 T84, [[Jan Maarten van Dijl]], University Medical Center Groningen, Dept.of Medical Microbiology, Groningen, The Netherlands
| |
| − | ** Intrinsic salt-sensitivity of minimal [[TatAC]] protein translocases in Gram-positive bacteria.
| |
| − |
| |
| − | * 9:15 – 9:30 T85, Veronique Broussolle, INRA, Université d’Avignon et des Pays de Vaucluse, Avignon, France
| |
| − | ** [[DEAD-box RNA helicases|RNA helicases]] are involved in the cold adaptation of ''Bacillus cereus'' ATCC 14579.
| |
| | | | |
| − | * 9:30 – 9:45 T86, Geremy Clair, INRA, Université d’Avignon et des Pays de Vaucluse, Avignon, France | + | * 12:00 – 12:20 – Requirements for the High-Frequency Activation of the Cryptic ''[[gudB]]'' Glutamate Dehydrogenase Gene in ''Bacillus subtilis'' |
| − | ** ''Bacillus cereus'' responds to low extracellular oxidoreduction potential by readjusting its proteome and secretome.
| + | ** Fabian Commichau (Georg-August-Universität Göttingen) |
| | | | |
| − | * 9:45 – 10:00 T87, [[Ulrike Mäder]], Ernst-Moritz-Arndt-University, Greifswald, Germany | + | * 12:20-12:40 – The Anaerobic Formation of Acetoin Regulated by the Transcriptional Regulator [[AlsR]] – Part of [[pH homeostasis|pH Homeostasis]] in ''Bacillus subtilis'' |
| − | ** Whole-transcriptome analysis of ''Bacillus subtilis'' under various environmental conditions.
| + | ** [[Elisabeth Härtig]] (TU Braunschweig) |
| | | | |
| − | ==Stress II==
| + | 12:40-14:00 – LUNCH |
| − | CHAIR: Terry Krulwich
| |
| | | | |
| − | * 10:30 – 10:45 T88, Axel Hartke, Lab. Microbiologie de l’Environnement, Université de Caen, Caen, France
| + | = Wednesday April 25th 2012 - Afternoon= |
| − | ** The oxidative stress response of Enterococci: Connection to virulence and antibiotic resistance.
| + | == EU BaSynthec Synthetic Biology Symposium == |
| | + | CHAIR: [[Kevin Devine]] |
| | | | |
| − | * 10:45 – 11:00 T89, Matthieu Jules, INRA, Micalis Institute, Jouy-en-Josas, France | + | * 14:00-14:10 – Introduction – [[Philippe Noirot]] (INRA) |
| − | ** Multi-omics, multi-laboratory study unravels ''Bacillus'' dynamic responses to environmental shifts. | + | * 14:10-14:40 – Enhanced Recombinant Protein Productivity by Genome Reduction in ''Bacillus subtilis'' - [[Naotake Ogasawara]] (Nara Institute) |
| | + | * 14:40-15:10 – Computational and Bioinformatics Approaches to Enabling Synthetic Biology - Anil Wipat (Newcastle University) |
| | + | * 15:10-15:40 – Highly Modified Peptides by Synthetic Biology Approaches - [[Oscar Kuipers]] (Groningen University) |
| | | | |
| − | * 11:00 – 11:15 T90, [[Erhard Bremer]], Microbiology, Philipps University of Marburg, Marburg, Germany | + | * 15:40-16:10 – COFFEE BREAK |
| − | ** Regulation of the synthesis of the osmoprotectant glycine betaine in ''B. subtilis'': Induction by choline and repression by a chemical chaperone.
| |
| | | | |
| − | * 11:15 – 11:30 T91, Mamta Rawat, California State University-Fresno, California, USA | + | * 16:10-16:40 – ''Bacillus subtilis'' Minimal Genome Work in Europe - [[Philippe Noirot]] (INRA) |
| − | ** Bacillithiol dependent detoxification in ''Staphylococcus aureus''. | + | * 16:40-17:10 – View of Novozymes on Synthetic Biology - Allen Kent Nielsen (Novozymes) |
| | + | * 17:10-17:40 – View of DSM on Synthetic Biology - [[Zoltan Pragai|Zoltán Prágai]] (DSM) |
| | + | * 17:40-17:50 – Wrap up / end of workshop – [[Philippe Noirot]] (INRA) |
| | | | |
| − | * 11:30 – 11:45 T92, Vanessa Khemici, Centre National de la Recherche Scientifique, Université de Toulouse, Toulouse, France
| |
| − | ** DNA replication stress triggers competence for genetic transformation in ''Streptococcus pneumoniae''.
| |
| | | | |
| − | ==Closing remarks==
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| | | | |
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