Difference between revisions of "PpsE"

From SubtiWiki
Jump to: navigation, search
Line 87: Line 87:
  
 
=Expression and regulation=
 
=Expression and regulation=
 
+
* '''Operon:''' ''[[ppsA]]-[[ppsB]]-[[ppsC]]-[[ppsD]]-[[ppsE]]'' {{PubMed|20817675}}
* '''Operon:'''  
 
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
Line 95: Line 94:
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[AbrB]]: transcription repression {{PubMed|20817675}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
Line 118: Line 118:
 
=References=
 
=References=
  
<pubmed>10471562,,9387222, </pubmed>
+
<pubmed>10471562,20817675,9387222, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:37, 15 September 2010

  • Description: plipastatin synthetase

Gene name ppsE
Synonyms
Essential no
Product plipastatin synthetase
Function production of the antibacterial compound plipastatin
MW, pI 144 kDa, 5.659
Gene length, protein length 3837 bp, 1279 aa
Immediate neighbours yngL, ppsD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PpsE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18300

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0713 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

K Tsuge, T Ano, M Hirai, Y Nakamura, M Shoda
The genes degQ, pps, and lpa-8 (sfp) are responsible for conversion of Bacillus subtilis 168 to plipastatin production.
Antimicrob Agents Chemother: 1999, 43(9);2183-92
[PubMed:10471562] [WorldCat.org] [DOI] (P p)

Valentina Tosato, Alessandra M Albertini, Michela Zotti, Sabrina Sonda, Carlo V Bruschi
Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168.
Microbiology (Reading): 1997, 143 ( Pt 11);3443-3450
[PubMed:9387222] [WorldCat.org] [DOI] (P p)