Difference between revisions of "PlsX"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_syn.html Fatty acid and phospholipid biosynthesis]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 5.492   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 5.492   

Revision as of 10:07, 16 February 2010

  • Description: acyl-acyl carrier protein (ACP):phosphate acyltransferase

Gene name plsX
Synonyms ylpD
Essential yes PubMed
Product acyl-acyl carrier protein (ACP):phosphate acyltransferase
Function biosynthesis of phospholipids
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid and phospholipid biosynthesis
MW, pI 35 kDa, 5.492
Gene length, protein length 999 bp, 333 aa
Immediate neighbours fapR, fabD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PlsX context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15890

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: plsX family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced if the cells experience an accumulation of malonyl-CoA (FapR) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Matsumoto lab PubMed
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References