PlsC

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  • Description: acyl-ACP:1-acylglycerolphosphate acyltransferase

Gene name plsC
Synonyms yhdO
Essential yes PubMed
Product acyl-ACP:1-acylglycerolphosphate acyltransferase
Function biosynthesis of phospholipids
MW, pI 21 kDa, 9.976
Gene length, protein length 597 bp, 199 aa
Immediate neighbours yhdN, yhdP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhdO context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU09540

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed unless the cells experience a lack of malonyl-CoA (FapR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gustavo E Schujman, Luciana Paoletti, Alan D Grossman, Diego de Mendoza
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Dev Cell: 2003, 4(5);663-72
[PubMed:12737802] [WorldCat.org] [DOI] (P p)