phrC

168

response regulator aspartate phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)

locus: BSU_03780

Molecular weight: 4.06 kDa

pI: 8.16

Protein length: 40 aa

Gene length: 123 bp

function: control of ComA activity

product: phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)

essential: no

ec: null

synonyms: phrC

List of homologs in different organisms

Gene

Coordinates: 429,963 → 430,085

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The protein

Catalyzed reaction/ biological activity

• binds to [protein|242632B27E0E3AB15777E9FBA3FC746D00CE97F9|rapC], this results in the inability of [protein|242632B27E0E3AB15777E9FBA3FC746D00CE97F9|rapC] to interact with [protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA] [Pubmed|12950917]

Protein family

• [wiki|phr family] (according to UniProt)

Structure

• [PDB|4GYO] (complex [protein|BC28167FE175BFD7DBF1B07C54D3512184B95B8F|rapJ]-[protein|C0B7845F55A16300EB37F026C817AEC4F3BA3B6F|phrC]) [Pubmed|23526881]
• [AF|P94416]

Biological materials

Mutant

• BKE03780 (Δ[gene|C0B7845F55A16300EB37F026C817AEC4F3BA3B6F|phrC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03780 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ACTTAGATTTCAATTTCATA,  downstream forward: _UP4_TAAGAACAAGCCCCTTCTCA
• BKK03780 (Δ[gene|C0B7845F55A16300EB37F026C817AEC4F3BA3B6F|phrC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03780 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ACTTAGATTTCAATTTCATA,  downstream forward: _UP4_TAAGAACAAGCCCCTTCTCA

References

Reviews

• 22024380,37042030

Original Publications

• 12950917,16816200,19202088,18375560,11267663,10464187,12850135,16091051,23526881,22511326