Difference between revisions of "PhrA"

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=References=
  
<pubmed>8643670,8730857,11923303,1378051,14651647,12618455, 12107147, 19380751  16091051</pubmed>
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<pubmed>8643670,8730857,11923303,1378051,14651647,12618455, 12107147, 19380751  16091051 20238180 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:59, 19 March 2010

Gene name phrA
Synonyms gsiAB
Essential no
Product phosphatase (RapA) inhibitor
Function control of sporulation initiation
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 4 kDa, 10.229
Gene length, protein length 132 bp, 44 aa
Immediate neighbours rapA, yjpA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU12440

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (4.2-fold) (CcpA) PubMed
    • repressed by casamino acids PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References