PhoD

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Gene name phoD
Synonyms ycbS
Essential no
Product phosphodiesterase/alkaline phosphatase
Function aquisition of phosphate upon phosphoate starvation
Gene expression levels in SubtiExpress: phoD
Interactions involving this protein in SubtInteract: PhoD
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 62 kDa, 8.394
Gene length, protein length 1668 bp, 556 aa
Immediate neighbours ycbR, tatAD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhoD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhoD expression.png
























Categories containing this gene/protein

phosphate metabolism

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU02620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A phosphate monoester + H2O = an alcohol + phosphate (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Oscar Kuipers, University of Groningen, The Netherlands Homepage

Your additional remarks

References