Difference between revisions of "Pgm"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
(Extended information on the protein)
Line 65: Line 65:
 
* '''Domains:'''  
 
* '''Domains:'''  
  
* '''Modification:''' phosphorylation  
+
* '''Modification:''' phosphorylation [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]
  
 
* '''Cofactor(s):''' 2 manganese ions per subunit
 
* '''Cofactor(s):''' 2 manganese ions per subunit

Revision as of 16:48, 8 January 2009

  • Description: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

Gene name pgm
Synonyms gpmI
Essential yes
Product 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Function isomerase
MW, pI 56,1 kDa, 5.21
Gene length, protein length 1533 bp, 511 amino acids
Immediate neighbours tpi, eno
Gene sequence (+200bp) Protein sequence
Genetic context
File:GenE context.gif












The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2-phospho-D-glycerate = 3-phospho-D-glycerate
  • Protein family: BPG-independent phosphoglycerate mutase family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation PubMed
  • Cofactor(s): 2 manganese ions per subunit
  • Effectors of protein activity:
  • Interactions: Pgm-PfkA
  • Localization: cytoplasm

Database entries

  • Structure:
  • Swiss prot entry: [3]
  • KEGG entry: [4]
  • E.C. number: [5]

Additional information

is pH sensitive

Expression and regulation

  • Regulation: neg. regulated by CggR PubMed, induced by sugar
  • Additional information:

Biological materials

Labs working on this gene/protein

Jörg Stülke, University of Göttingen, Germany Homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed