Difference between revisions of "PghC"

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(The protein)
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** hyhrolysis of polyglutamic acid {{PubMed|26158264}}
  
 
* '''Protein family:''' UPF0714 family (according to Swiss-Prot)
 
* '''Protein family:''' UPF0714 family (according to Swiss-Prot)
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[PghB]], [[PghL]], [[PghZ]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:''' DUF867 [http://pfam.xfam.org/family/PF05908], [[gamma-PGA hydrolase domain]] {{PubMed|26158264}}
  
 
* '''Modification:'''
 
* '''Modification:'''

Revision as of 08:41, 13 July 2015

  • Description: phage-derived gamma polyglutamic acid hydrolase

Gene name ymaC
Synonyms
Essential no
Product phage-derived gamma polyglutamic acid hydrolase
Function polyglutamic acid degradation
Gene expression levels in SubtiExpress: ymaC
MW, pI 26 kDa, 8.295
Gene length, protein length 705 bp, 235 aa
Immediate neighbours ymzE/2, ymaD
Sequences Protein DNA DNA_with_flanks
Genetic context
YmaC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YmaC expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17270

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hyhrolysis of polyglutamic acid PubMed
  • Protein family: UPF0714 family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefania Mamberti, Paola Prati, Paolo Cremaschi, Claudio Seppi, Carlo F Morelli, Alessandro Galizzi, Massimo Fabbi, Cinzia Calvio
γ-PGA Hydrolases of Phage Origin in Bacillus subtilis and Other Microbial Genomes.
PLoS One: 2015, 10(7);e0130810
[PubMed:26158264] [WorldCat.org] [DOI] (I e)