Difference between revisions of "PgcM"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34550 pgcM]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34550 pgcM]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=pgcM pgcM]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 4.76   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 4.76   

Revision as of 11:44, 7 January 2014

  • Description: β-phosphoglucomutase/ glucose-1-phosphate phosphodismutase

Gene name pgcM
Synonyms yvdM
Essential no
Product beta-phosphoglucomutase
(EC 5.4.2.6 and EC 2.7.1.41)
Function starch and maltodextrin utilization
Gene expression levels in SubtiExpress: pgcM
Metabolic function and regulation of this protein in SubtiPathways:
pgcM
MW, pI 24 kDa, 4.76
Gene length, protein length 678 bp, 226 aa
Immediate neighbours clpP, malL
Sequences Protein DNA DNA_with_flanks
Genetic context
PgcM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PgcM expression.png




























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU34550

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate (according to Swiss-Prot)
  • Protein family: CbbY/cbbZ/gph/yieH family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3NAS; 1ZOL (from Lactococcus lactis, 48% identity, 66% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

L R Mesak, M K Dahl
Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis.
Arch Microbiol: 2000, 174(4);256-64
[PubMed:11081794] [WorldCat.org] [DOI] (P p)