Difference between revisions of "PgcM"

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(Database entries)
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ZOL 1ZOL] (from ''Lactococcus lactis'', 48% identity, 66% similarity) {{PubMed|15996095}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O06995 O06995]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O06995 O06995]

Revision as of 14:57, 17 February 2010

  • Description: beta-phosphoglucomutase

Gene name pgcM
Synonyms yvdM
Essential no
Product beta-phosphoglucomutase
(EC 5.4.2.6 and EC 2.7.1.41)
Function starch and maltodextrin utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 24 kDa, 4.76
Gene length, protein length 678 bp, 226 aa
Immediate neighbours clpP, malL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PgcM context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU34550

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate (according to Swiss-Prot)
  • Protein family: CbbY/cbbZ/gph/yieH family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1ZOL (from Lactococcus lactis, 48% identity, 66% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

L R Mesak, M K Dahl
Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis.
Arch Microbiol: 2000, 174(4);256-64
[PubMed:11081794] [WorldCat.org] [DOI] (P p)