Difference between revisions of "PfeT"

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|style="background:#ABCDEF;" align="center"|'''Function''' || zinc uptake
 
|style="background:#ABCDEF;" align="center"|'''Function''' || zinc uptake
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13850 zosA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13850 zosA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 68 kDa, 4.934   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 68 kDa, 4.934   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[stoA]]'', ''[[papB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[stoA]]'', ''[[papB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13258&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13850 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13850 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13850 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykvW_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykvW_context.gif]]

Revision as of 12:40, 13 May 2013

  • Description: zinc transporter

Gene name zosA
Synonyms ykvW
Essential no
Product P-type zinc-transporting ATPase
Function zinc uptake
Gene expression levels in SubtiExpress: zosA
MW, pI 68 kDa, 4.934
Gene length, protein length 1911 bp, 637 aa
Immediate neighbours stoA, papB
Sequences Protein DNA Advanced_DNA
Genetic context
YkvW context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ZosA expression.png















Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU13850

Phenotypes of a mutant

    • reduced genetic competence, can be rescued by the addition of excess zinc PubMed
    • reduced expression of comK, control is exerted at the post-transcriptional level and can be rescued by the addition of excess zinc PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + H2O + Zn2+(In) = ADP + phosphate + Zn2+(Out) (according to Swiss-Prot) P-type zinc-transporting ATPase PubMed
  • Protein family: Type IB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: induced by hydrogen peroxide (PerR) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References