Difference between revisions of "PdxK"

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(Basic information/ Evolution)
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* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2IB5 2IB5]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2IB5 2IB5]
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39610 P39610]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39610 P39610]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38020]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38020]

Revision as of 15:07, 20 July 2009

  • Description: pyridoxine, pyridoxal, and pyridoxamine kinase

Gene name pdxK
Synonyms ywdB, ipa-52r, thiD
Essential no
Product pyridoxine, pyridoxal, and pyridoxamine kinase
Function biosynthesis of pyridoxal phosphate
MW, pI 28 kDa, 4.922
Gene length, protein length 813 bp, 271 aa
Immediate neighbours ywdC, ywdA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThiD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine (according to Swiss-Prot)
  • Protein family: thiD family (according to Swiss-Prot)
  • Paralogous protein(s): ThiD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References