Pdp

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  • Description: pyrimidine nucleoside phosphorylase

Gene name pdp
Synonyms
Essential no
Product pyrimidine nucleoside phosphorylase
Function pyrimidine interconversion
MW, pI 46 kDa, 4.765
Gene length, protein length 1299 bp, 433 aa
Immediate neighbours hutM, nupC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Pdp context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU39400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A pyrimidine nucleoside + phosphate = a pyrimidine base + alpha-D-ribose 1-phosphate (according to Swiss-Prot)
  • Protein family: thymidine/pyrimidine-nucleoside phosphorylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1BRW (Geobacillus stearothermophilus)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed