PdeH

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  • Description: unknown

Gene name yuxH
Synonyms comB, yufA
Essential no
Product unknown
Function unknown
MW, pI 47 kDa, 5.36
Gene length, protein length 1227 bp, 409 aa
Immediate neighbours yuzC, pncB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YuxH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YuxH expression.png
























Categories containing this gene/protein

metabolism of signalling nucleotides

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU31740

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate (according to Swiss-Prot)
  • Protein family: comB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Masaya Fujita, José Eduardo González-Pastor, Richard Losick
High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis.
J Bacteriol: 2005, 187(4);1357-68
[PubMed:15687200] [WorldCat.org] [DOI] (P p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

Y Weinrauch, N Guillen, D A Dubnau
Sequence and transcription mapping of Bacillus subtilis competence genes comB and comA, one of which is related to a family of bacterial regulatory determinants.
J Bacteriol: 1989, 171(10);5362-75
[PubMed:2507523] [WorldCat.org] [DOI] (P p)