Difference between revisions of "PdeH"

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(The protein)
(Biological materials)
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=Biological materials =
 
=Biological materials =
  
* '''Mutant:'''
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* '''Mutant:''' GP1590 (kan) available in [[Stülke]] lab
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''

Revision as of 11:36, 13 August 2013

  • Description: c-di-GMP degrading phosphodiesterase

Gene name pdeH
Synonyms yuxH, comB, yufA
Essential no
Product c-di-GMP degrading phosphodiesterase
Function degradation of c-di-GMP
Gene expression levels in SubtiExpress: pdeH
MW, pI 47 kDa, 5.36
Gene length, protein length 1227 bp, 409 aa
Immediate neighbours yuzC, pncB
Sequences Protein DNA DNA_with_flanks
Genetic context
YuxH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YuxH expression.png















Categories containing this gene/protein

metabolism of signalling nucleotides, motility and chemotaxis

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU31740

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • degradation of c-di-GMP PubMed
  • Protein family: comB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • contains an EAL domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1590 (kan) available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References