pbuG

168

hypoxanthin/ guanine permease

locus: BSU_06370

Molecular weight: 46.03 kDa

pI: 8.81

Protein length: 440 aa

Gene length: 1323 bp

function: hypoxanthine and guanine uptake

product: hypoxanthin/ guanine permease

essential: no

ec: null

synonyms: pbuG, yebB

List of homologs in different organisms, belongs to COG2252 (Galperin et al., 2021)

Gene

Coordinates: 694,662  695,984

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The protein

Protein family

• [wiki|xanthine/uracil permease family] (according to UniProt)

Structure

• [PDB|2EEW] (the pbuG riboswitch, U47c mutant, bound to hypoxanthine)
• [AF|O34987]

Paralogous protein(s)

• [protein|62AC66725C55B9E5FBBEB4EC43A88F7081B74D5C|pbuO]

[wiki|Localization]

• membrane [Pubmed|18763711]

Biological materials

Mutant

• BKE06370 ([gene|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A|pbuG]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06370 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGCTATTTGACTCCCTTC,  downstream forward: _UP4_TAAGGAATGAAAAACCAGCT
• BKK06370 ([gene|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A|pbuG]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06370 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGCTATTTGACTCCCTTC,  downstream forward: _UP4_TAAGGAATGAAAAACCAGCT

References

• 11591660,12923093,11591660,18763711,12923093,12787499,35622174