Difference between revisions of "PbpH"

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(This gene is a member of the following regulons)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''  
 +
** part of the [[cell wall biosynthetic complex]] {{PubMed|21636744,21636745}}
  
 
* '''Localization:''' cell membrane (according to Swiss-Prot)
 
* '''Localization:''' cell membrane (according to Swiss-Prot)

Revision as of 05:18, 11 July 2011

Gene name pbpH
Synonyms ykuA
Essential no
Product penicillin-binding protein H
Function formation of a rod-shaped peptidoglycan cell wall
MW, pI 76 kDa, 8.888
Gene length, protein length 2055 bp, 685 aa
Immediate neighbours ykwD, kinA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YkuA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall synthesis, membrane proteins

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU13980

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transpeptidase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Yuping Wei, Teresa Havasy, Derrell C McPherson, David L Popham
Rod shape determination by the Bacillus subtilis class B penicillin-binding proteins encoded by pbpA and pbpH.
J Bacteriol: 2003, 185(16);4717-26
[PubMed:12896990] [WorldCat.org] [DOI] (P p)