Difference between revisions of "PatA"

From SubtiWiki
Jump to: navigation, search
Line 8: Line 8:
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''uat ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''uat ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|23109554}}
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Product''' || aminotransferase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || aminotransferase
Line 37: Line 37:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
+
<br/><br/>
<br/><br/><br/><br/>
 
  
 +
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[Cell wall synthesis]]}},
 +
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
 +
{{SubtiWiki category|[[Biosynthesis of cell wall components]]}},
 +
{{SubtiWiki category|[[essential genes]]}}
  
<br/><br/><br/><br/><br/><br/>
 
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}
 
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
Line 56: Line 56:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
+
* essential {{PubMed|23109554}}
 
=== Database entries ===
 
=== Database entries ===
  
Line 139: Line 139:
  
 
=References=
 
=References=
 
+
<pubmed> 23109554 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:58, 31 October 2012

  • Description: aminotransferase

Gene name patA
Synonyms uat
Essential yes PubMed
Product aminotransferase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: patA
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 43 kDa, 6.005
Gene length, protein length 1176 bp, 392 aa
Immediate neighbours kinA, cheV
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PatA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PatA expression.png















Categories containing this gene/protein

Cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes


This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kosei Tanaka, Christopher S Henry, Jenifer F Zinner, Edmond Jolivet, Matthew P Cohoon, Fangfang Xia, Vladimir Bidnenko, S Dusko Ehrlich, Rick L Stevens, Philippe Noirot
Building the repertoire of dispensable chromosome regions in Bacillus subtilis entails major refinement of cognate large-scale metabolic model.
Nucleic Acids Res: 2013, 41(1);687-99
[PubMed:23109554] [WorldCat.org] [DOI] (I p)