Difference between revisions of "PatA"

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(Basic information/ Evolution)
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14000 patA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14000 patA]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=patA patA]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 6.005   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 6.005   

Revision as of 10:39, 7 January 2014

  • Description: aminotransferase

Gene name patA
Synonyms uat
Essential yes PubMed
Product aminotransferase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: patA
Metabolic function and regulation of this protein in SubtiPathways:
patA
MW, pI 43 kDa, 6.005
Gene length, protein length 1176 bp, 392 aa
Immediate neighbours kinA, ykzT
Sequences Protein DNA DNA_with_flanks
Genetic context
PatA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PatA expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: N-acetyl-2-amino-6-ketopimelate --> N-acetyl-L,L-2,6-diaminopimelate PubMed
  • Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed