PapB

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  • Description: Xaa-Pro amino-peptidase

Gene name papB
Synonyms ykvY
Essential no
Product Xaa-Pro amino-peptidase
Function degradation of proline-containing peptides
Gene expression levels in SubtiExpress: papB
Metabolic function and regulation of this protein in SubtiPathways:
papB
MW, pI 40 kDa, 5.171
Gene length, protein length 1089 bp, 363 aa
Immediate neighbours zosA, ykvZ
Sequences Protein DNA DNA_with_flanks
Genetic context
YkvY context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkvY expression.png















Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, coping with hyper-osmotic stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU13860

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M24B family (according to Swiss-Prot)
  • Paralogous protein(s): PapA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3Q6D (B. anthracis Xaa-Pro dipeptidase, 35% identity, 55% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Adrienne Zaprasis, Jeanette Brill, Marietta Thüring, Guido Wünsche, Magnus Heun, Helena Barzantny, Tamara Hoffmann, Erhard Bremer
Osmoprotection of Bacillus subtilis through import and proteolysis of proline-containing peptides.
Appl Environ Microbiol: 2013, 79(2);576-87
[PubMed:23144141] [WorldCat.org] [DOI] (I p)