papB

168

Xaa-Pro amino-peptidase

locus: BSU_13860

Molecular weight: 40.18 kDa

pI: 5.17

Protein length: 363 aa

Gene length: 1092 bp

function: degradation of proline-containing peptides

product: Xaa-Pro amino-peptidase

essential: no

ec: 3.4.11.9

synonyms: papB, ykvY

List of homologs in different organisms, belongs to COG0006 (Galperin et al., 2021)

Gene

Coordinates: 1,453,691 → 1,454,782

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The protein

Protein family

• peptidase M24B family (with [protein|33886A1EAC13B684E92BF94201C46617AD2844B3|papA], according to UniProt)

Structure

• [PDB|3Q6D] (''B. anthracis'' Xaa-Pro dipeptidase, 35% identity, 55% similarity)
• [AF|O31689]

Paralogous protein(s)

• [protein|33886A1EAC13B684E92BF94201C46617AD2844B3|papA]

Biological materials

Mutant

• MGNA-B330 (ykvY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1329 NBRP B. subtilis, Japan]
• BKE13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC,  downstream forward: _UP4_TAATAGAAATAAAAAAGGAC
• BKK13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13860 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC,  downstream forward: _UP4_TAATAGAAATAAAAAAGGAC

References

• 23144141