Difference between revisions of "PadR"

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(Extended information on the protein)
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[transcription factors and their control]]}},
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{{SubtiWiki category|[[resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]]}}
 
=The protein=
 
=The protein=
  

Revision as of 18:37, 30 November 2010

  • Description: repressor of yveF-yveG-padC, induction occurs by binding of phenolic acids,stress response

Gene name padR
Synonyms yfiO
Essential no
Product transcriptional repressor
Function regulation of the phenolic acid stress response
MW, pI 21 kDa, 7.231
Gene length, protein length 546 bp, 182 aa
Immediate neighbours yfiN, lipB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PadR context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU08340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: phenolic acid acts as molecular inducer and releases PadR from the yveF-yveG-padC promoter PubMed
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: padR (according to DBTBS)
  • Regulation: weak constitutive expression
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ngoc Phuong Tran, Jerôme Gury, Véronique Dartois, Thi Kim Chi Nguyen, Hélène Seraut, Lise Barthelmebs, Patrick Gervais, Jean-François Cavin
Phenolic acid-mediated regulation of the padC gene, encoding the phenolic acid decarboxylase of Bacillus subtilis.
J Bacteriol: 2008, 190(9);3213-24
[PubMed:18326577] [WorldCat.org] [DOI] (I p)