Difference between revisions of "PabA"

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(Expression and regulation)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[pabB]]-[[pabA]]-[[pabC]]-[[sul]]-[[folB]]-[[folK]]-[[yazB]]-[[yacF]]-[[lysS]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9084182 PubMed]
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9084182 PubMed]
  
 
* '''Regulation:''' translation repressed by tryptophan ([[MtrB]])
 
* '''Regulation:''' translation repressed by tryptophan ([[MtrB]])

Revision as of 19:35, 2 May 2009

  • Description: para-aminobenzoate synthase (subunit B)/ anthranilate synthase (subunit II)

Gene name pabA
Synonyms trpG, trpX
Essential no
Product para-aminobenzoate synthase (subunit B)/
anthranilate synthase (subunit II)
glutamine amidotransferase (subunit B)
and anthranilate synthase (subunit II)
Function biosynthesis of folate and tryptophan
MW, pI 21 kDa, 4.782
Gene length, protein length 582 bp, 194 aa
Immediate neighbours pabB, pabC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PabA context.gif
This image was kindly provided by SubtiList






The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number: (EC 4.1.3.- and EC 4.1.3.27)

Additional information

Expression and regulation

  • Regulation: translation repressed by tryptophan (MtrB)
  • Regulatory mechanism: MtrB: translation termination
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed