Difference between revisions of "PTS"

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=The PEP:Sugar Phosphotransferase System=
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#REDIRECT [[phosphotransferase systems]]
 
 
'''The PTS is a sugar transport system that couples the transport of a sugar to its phosphorylation. The phosphate group is derived from phosphoenolpyruvate (PEP) and transferred via the general PTS proteins [[ptsI|Enzyme I]] ([[ptsI|EI]]) and [[ptsH|HPr]] to the substrate-specific Enzymes II (EII) to the incoming sugars.'''
 
 
 
'''In addition to its role in sugar transport, the PTS is also involved in the regulation of carbon metabolism.'''
 
 
 
==General PTS proteins==
 
* [[ptsI|Enzyme I]]
 
* [[ptsH|HPr]]
 
 
 
==Sugar specific PTS proteins==
 
* [[PtsG]]: glucose permease, EIICBA
 
* [[GamP]]: glucosamine permease, EIICBA
 
* [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
 
* [[MtlA]], [[MtlF]]: mannitol permease
 
* [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease
 
* [[TreP]]: trehalose permease
 
* [[MalP]]: maltose permease
 
* [[FruA]]: fructose permease
 
* [[ManP]]: mannose permease
 
* [[YpqE]]: unknown EIIA component
 
* [[LevD]], [[LevE]], [[LevF]], [[LevG]]: fructose permease
 
* [[SacP]]: sucrose permease (high affinity)
 
* [[SacY]]: sucrose permease (low affinity)
 
* [[LicA]], [[LicB]], [[LicC]]: lichenan permease
 
* [[BglP]]: ß-glucoside permease
 
* [[YyzE]]: unknown PTS protein
 
* [[MtlF]]
 
* [[YwbA]]: unknown EIIC component
 
 
 
==Proteins closely related to the PTS==
 
* [[Crh]]: [[ptsH|HPr]]-like protein with exculsively regulatory functions (His-15 is not conserved
 
* [[HprK]]: [[ptsH|HPr]]-kinase, key factor for carbon catabolite repression
 
 
 
==Non-PTS proteins controlled by PTS-dependent phosphorylation==
 
* [[PRD-containing transcription factors]]
 
* [[GlpK]]
 
 
 
==The PTS in [[SubtiPathways|''Subti''Pathways]]==
 
* [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
 
* [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
 
 
 
==Related Lists==
 
* [[PRD-containing transcription factors]]
 
* [[transport proteins]]
 
* [[trigger enzymes]]
 
 
 
==Relevant Reviews==
 
<pubmed>17158705 9871918 9663674 10627040  </pubmed>
 

Latest revision as of 11:13, 12 November 2010