opuCB

168

glycine betaine/carnitine/choline/arsenobetaine/arsenocholine [wiki|ABC transporter]

locus: BSU_33820

Molecular weight: 23.00 kDa

pI: 9.7

Protein length: 217 aa

Gene length: 654 bp

function: compatible solute transport

product: glycine betaine/carnitine/choline/arsenobetaine/arsenocholine [wiki|ABC transporter]

essential: no

synonyms: opuCB, yvbD

List of homologs in different organisms, belongs to COG1174 (Galperin et al., 2021)

Gene

Coordinates: 3,469,184  3,469,837

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The protein

Catalyzed reaction/ biological activity

• uptake of glycine betaine, arsenocholine and arsenobetaine [pubmed|29159878]

Protein family

• [wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
• [wiki|CysTW subfamily] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transmembrane type-1 domain] (aa 19-198) (according to UniProt)

Structure

• [AF|O34878]

Paralogous protein(s)

• [protein|70B45E7428DB1F6AEF7D2FE3062CC86BE96674FC|opuBB]

[wiki|Localization]

• cell membrane [Pubmed|10092453]

Biological materials

Mutant

• BKE33820 ([gene|83C45215AC86FACB08CF36EB5F9E6B076D7D0F0F|opuCB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTAAAAGAGCTCCTCC,  downstream forward: _UP4_TCGTAAGGAGTTGGCACTGT
• BKK33820 ([gene|83C45215AC86FACB08CF36EB5F9E6B076D7D0F0F|opuCB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTTAAAAGAGCTCCTCC,  downstream forward: _UP4_TCGTAAGGAGTTGGCACTGT

References

Reviews

• 27935846

Original Publications

• 36815589,10092453,9925583,10216873,21296969,23960087,23646920,29159878