Difference between revisions of "OpcR"
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| − | * '''Description:''' | + | * '''Description:''' transcriptional repressor of the ''[[opuBA]]-[[opuBB]]-[[opuBC]]-[[opuBD]]'' and ''[[opuCA]]-[[opuCB]]-[[opuCC]]-[[opuCD]]'' operons<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''opcR'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvbF '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || choline-responsible transcription repressor |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of choline uptake |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33840 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33840 opcR] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 5.837 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 5.837 | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, |
| + | {{SubtiWiki category|[[transcription factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[coping with hyper-osmotic stress]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | = The [[OpcR regulon]] = | ||
=The gene= | =The gene= | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | + | ** transcriptional repression of the ''[[opuBA]]-[[opuBB]]-[[opuBC]]-[[opuBD]]'' and ''[[opuCA]]-[[opuCB]]-[[opuCC]]-[[opuCD]]'' operons in the presence of choline {{PubMed|23960087}} | |
* '''Protein family:''' | * '''Protein family:''' | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[YvaV]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 108: | Line 107: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvbF_3471266_3471823_1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvbF_3471266_3471823_1 opcR] {{PubMed|22383849}} |
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 23960087 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:40, 21 August 2013
- Description: transcriptional repressor of the opuBA-opuBB-opuBC-opuBD and opuCA-opuCB-opuCC-opuCD operons
| Gene name | opcR |
| Synonyms | yvbF |
| Essential | no |
| Product | choline-responsible transcription repressor |
| Function | regulation of choline uptake |
| Gene expression levels in SubtiExpress: opcR | |
| MW, pI | 21 kDa, 5.837 |
| Gene length, protein length | 555 bp, 185 aa |
| Immediate neighbours | opuCA, yvbG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, transcription factors and their control, coping with hyper-osmotic stress
This gene is a member of the following regulons
The OpcR regulon
The gene
Basic information
- Locus tag: BSU33840
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YvaV
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34709
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Chun-Hao Lee, Tien-Yu Wu, Gwo-Chyuan Shaw
Involvement of OpcR, a GbsR-type transcriptional regulator, in negative regulation of two evolutionarily closely related choline uptake genes in Bacillus subtilis.
Microbiology (Reading): 2013, 159(Pt 10);2087-2096
[PubMed:23960087]
[WorldCat.org]
[DOI]
(I p)
