Difference between revisions of "NusB"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[nusB]]-[[folD]]'' | + | * '''Operon:''' ''[[nusB]]-[[folD]]'' {{PubMed|2536750,11591660}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed in the presence of purine nucleotides ([[PurR]]) {{PubMed|2536750,11591660}} | ||
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ||
| − | |||
| − | |||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | + | ** [[PurR]]: transcription repression (molecular inducer: PRPP) {{PubMed|2536750,11591660}} | |
| − | ** [[PurR]]: transcription repression (molecular inducer: PRPP) | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 20:05, 20 November 2009
- Description: probable transcription termination
| Gene name | nusB |
| Synonyms | yqhZ |
| Essential | no |
| Product | unknown |
| Function | unknown |
| MW, pI | 14 kDa, 4.757 |
| Gene length, protein length | 393 bp, 131 aa |
| Immediate neighbours | folD, yqhY |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU24320
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nusB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54520
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
H H Saxild, K Brunstedt, K I Nielsen, H Jarmer, P Nygaard
Definition of the Bacillus subtilis PurR operator using genetic and bioinformatic tools and expansion of the PurR regulon with glyA, guaC, pbuG, xpt-pbuX, yqhZ-folD, and pbuO.
J Bacteriol: 2001, 183(21);6175-83
[PubMed:11591660]
[WorldCat.org]
[DOI]
(P p)
