Difference between revisions of "NupG"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1191 bp, 397 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1191 bp, 397 aa  
 
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxjB]]'', ''[[yxiT]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxjB]]'', ''[[yxiT/1]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15928&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15928&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''

Revision as of 11:52, 5 December 2012

  • Description: purine nucleoside transporter

Gene name nupG
Synonyms yxjA
Essential no
Product purine nucleoside transporter
Function purine uptake
Gene expression levels in SubtiExpress: nupG
MW, pI 43 kDa, 7.757
Gene length, protein length 1191 bp, 397 aa
Immediate neighbours yxjB, yxiT/1
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxjA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NupG expression.png


























Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of nucleotides, membrane proteins

This gene is a member of the following regulons

G-box

The gene

Basic information

  • Locus tag: BSU39020

Phenotypes of a mutant

  • a nupN nupG double mutant is unable to utilize externally provided guanosine PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: SLC28A transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: nupG
  • Sigma factor:
  • Regulation:
    • expression activated by glucose (4.3 fold) PubMed
    • repressed by hypoxanthine and guanine, PurR-independent, G-boxPubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References