nupC

168

pyrimidine nucleoside transport protein

locus: BSU_39410

Molecular weight: 42.37 kDa

pI: 9.32

Protein length: 393 aa

Gene length: 1182 bp

function: pyrimidine uptake

product: pyrimidine nucleoside transport protein

essential: no

synonyms: nupC

List of homologs in different organisms, belongs to COG1972 (Galperin et al., 2021)

Gene

Coordinates: 4,050,340  4,051,521

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The protein

Protein family

• concentrative nucleoside transporter (CNT) (TC 2.A.41) family (with [protein|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK] and [protein|C333F405F597FF260FFA0EC616B8CF6BF454815B|nupG], according to UniProt)

Structure

• [PDB|3TIJ] (from Vibrio cholerae, 33% identity) [pubmed|22407322]
• [AF|P39141]

[wiki|Localization]

• membrane protein [Pubmed|18763711]

Biological materials

Mutant

• BKE39410 ([gene|4F718681A7AD0C86B2551248570F493AC0B2E7E9|nupC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGTGTTTCTCCTTTAT,  downstream forward: _UP4_TGAACTTAATCGAAAAGGAT
• BKK39410 ([gene|4F718681A7AD0C86B2551248570F493AC0B2E7E9|nupC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39410 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGTGTTTCTCCTTTAT,  downstream forward: _UP4_TGAACTTAATCGAAAAGGAT

References

• 11065368,8550462,10074062,18763711,10666464,22407322