Difference between revisions of "NrgB"

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=References=
 
=References=
 
==Reviews==
 
==Reviews==
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<pubmed>10637624 18182294 11238986 </pubmed>
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==Original Publications==
 
==Original Publications==
 
<pubmed>12823818,,8799114,17001076 , 14600241 ,8282685 ,1670935 17220269</pubmed>
 
<pubmed>12823818,,8799114,17001076 , 14600241 ,8282685 ,1670935 17220269</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 21:16, 19 January 2010

  • Description: nitrogen-regulated PII-like protein

Gene name nrgB
Synonyms glnK
Essential no
Product nitrogen-regulated PII-like protein
Function regulation of ammonium uptake
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 12 kDa, 8.825
Gene length, protein length 348 bp, 116 aa
Immediate neighbours nrgA, bcrC
Gene sequence (+200bp) Protein sequence
Genetic context
NrgB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU36520

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: P(II) protein family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot), membrane

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by ammonium limitation
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • Regulatory mechanism: transcription activation by TnrA
  • Additional information:

Biological materials

  • Mutant: GP259 (cat), GP255 (nrgAB, cat), both available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:

Labs working on this gene/protein

Susan Fisher, Boston, USA homepage

Your additional remarks

References

Reviews

Karl Forchhammer
P(II) signal transducers: novel functional and structural insights.
Trends Microbiol: 2008, 16(2);65-72
[PubMed:18182294] [WorldCat.org] [DOI] (P p)

T Arcondéguy, R Jack, M Merrick
P(II) signal transduction proteins, pivotal players in microbial nitrogen control.
Microbiol Mol Biol Rev: 2001, 65(1);80-105
[PubMed:11238986] [WorldCat.org] [DOI] (P p)

G Thomas, G Coutts, M Merrick
The glnKamtB operon. A conserved gene pair in prokaryotes.
Trends Genet: 2000, 16(1);11-4
[PubMed:10637624] [WorldCat.org] [DOI] (P p)


Original Publications