nrdEB

nrdEB
168

similar to ribonucleoside-diphosphate reductase (alpha subunit)

locus
BSU_20060
Molecular weight
27.82 kDa
pI
6.39
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
nrdEB, yosN

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1372 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,162,108 → 2,165,614
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The protein
Catalyzed reaction/ biological activity
[thioredoxin]-disulfide + 2'-deoxyribonucleoside 5'-diphosphate + H2O --> [thioredoxin]-dithiol + ribonucleoside 5'-diphosphate (according to UniProt)
Protein family
ribonucleoside diphosphate reductase large chain family (with [protein|3B68CE8E9A35997B45E437A316996D585E43B76B|nrdE], according to UniProt)
[wiki|Domains]
DOD-type homing endonuclease domain (aa 503-654) (according to UniProt)
Structure
[AF|O31875]
Paralogous protein(s)
[protein|3B68CE8E9A35997B45E437A316996D585E43B76B|nrdE]
Biological materials
Mutant
BKE20060 (Δ[gene|FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D|nrdEB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE20060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATTGAGCTTGATCCAA,  downstream forward: _UP4_TAATAGGTACGTTTACGTTT
BKK20060 (Δ[gene|FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D|nrdEB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK20060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATTGAGCTTGATCCAA,  downstream forward: _UP4_TAATAGGTACGTTTACGTTT
References
21498918,11470879,16621400,9465078

FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D

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Time of last update: 2024-03-28 13:01:03

Author of last update: Melvin.boenninger