NicK

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  • Description: DNA relaxase, similar to transposon protein

Gene name nicK
Synonyms ydcR
Essential no
Product DNA relaxase, similar to transposon protein
Function conjugation of ICE BS1
MW, pI 40 kDa, 5.131
Gene length, protein length 1056 bp, 352 aa
Immediate neighbours ydcQ , ydcS
Gene sequence (+200bp) Protein sequence
Genetic context
YdcR context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

mobile genetic elements

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04870

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: plasmid replication initiation factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Elisabeth Grohmann
Autonomous plasmid-like replication of Bacillus ICEBs1: a general feature of integrative conjugative elements?
Mol Microbiol: 2010, 75(2);261-3
[PubMed:19943906] [WorldCat.org] [DOI] (I p)

Original Publications

Catherine A Lee, Ana Babic, Alan D Grossman
Autonomous plasmid-like replication of a conjugative transposon.
Mol Microbiol: 2010, 75(2);268-79
[PubMed:19943900] [WorldCat.org] [DOI] (I p)

Catherine A Lee, Alan D Grossman
Identification of the origin of transfer (oriT) and DNA relaxase required for conjugation of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
J Bacteriol: 2007, 189(20);7254-61
[PubMed:17693500] [WorldCat.org] [DOI] (P p)