Difference between revisions of "NhaC"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[transporters/ other]]}},
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{{SubtiWiki category|[[metal ion homeostasis (K, Na, Ca, Mg)]]}},
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{{SubtiWiki category|[[pH homeostasis]]}},
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{{SubtiWiki category|[[membrane proteins]]}}
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= This gene is a member of the following [[regulons]] =
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=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[transporters/ other]]}},
 
{{SubtiWiki category|[[metal ion homeostasis (K, Na, Ca, Mg)]]}},
 
{{SubtiWiki category|[[pH homeostasis]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 18:05, 8 December 2010

  • Description: Na+/H+ antiporter

Gene name nhaC
Synonyms yheL
Essential no
Product Na+/H+ antiporter
Function pH homeostasis
MW, pI 47 kDa, 7.874
Gene length, protein length 1359 bp, 453 aa
Immediate neighbours dat, nhaX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NhaC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), pH homeostasis, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU09680

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)
  • Paralogous protein(s): MleN

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
    • NhaX: transcription activation (probably) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Z Prágai, C Eschevins, S Bron, C R Harwood
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.
J Bacteriol: 2001, 183(8);2505-15
[PubMed:11274110] [WorldCat.org] [DOI] (P p)