NdoAI

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Gene name ndoAI
Synonyms ydcD
Essential no
Product antitoxin
Function inhibition of NdoA
Gene expression levels in SubtiExpress: ndoAI
Interactions involving this protein in SubtInteract: NdoAI
MW, pI 10 kDa, 6.138
Gene length, protein length 279 bp, 93 aa
Immediate neighbours alr, ndoA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdcD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NdoAI expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04650

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: mazE/ndoAI family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361] [WorldCat.org] [DOI] (P p)

Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409] [WorldCat.org] [DOI] (P p)