Difference between revisions of "NatR"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[natA]]-[[natB]]'' operon
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[natA]]-[[natB]]'' operon
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02740 natR]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02740 natR]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NatR NatR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NatR NatR]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[natK]]'', ''[[natA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[natK]]'', ''[[natA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12068&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02740 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yccH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yccH_context.gif]]

Revision as of 12:04, 13 May 2013

Gene name natR
Synonyms yccH
Essential no
Product two-component response regulator
Function regulation of the natA-natB operon
Gene expression levels in SubtiExpress: natR
Interactions involving this protein in SubtInteract: NatR
MW, pI 26 kDa, 6.614
Gene length, protein length 699 bp, 233 aa
Immediate neighbours natK, natA
Sequences Protein DNA Advanced_DNA
Genetic context
YccH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NatR expression.png

























Categories containing this gene/protein

metal ion homeostasis (K, Na, Ca, Mg), transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

The NatR regulon:

The gene

Basic information

  • Locus tag: BSU02740

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by NatK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: natR (according to DBTBS)
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mitsuo Ogura, Kensuke Tsukahara, Kentaro Hayashi, Teruo Tanaka
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
Microbiology (Reading): 2007, 153(Pt 3);667-675
[PubMed:17322186] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)